| 3/25/2022 |
Matching-adjusted indirect treatment comparison of chimeric antigen receptor T-cell therapies for third-line or later treatment of relapsed or refractory large B-cell lymphoma: lisocabtagene maraleucel versus tisagenlecleucel |
biomedcentral.com |
Research- Open Access- Published:]Matching-adjusted indirect treatment comparison of chimeric antigen receptor T-cell therapies for third-line or later treatment of relapsed or refractory large B-cell lymphoma: lisocabtagene maraleucel versus tisagenlecleucel 17 (2022) [Cite this articleAbstractBackgroundThere are no head-to-head clinical studies comparing chimeric antigen receptor (CAR) T-cell therapies for the treatment of relapsed or refractory aggressive large B-cell lymphomas ... |
| 3/24/2022 |
Best statins for reducing cardiovascular risk in people with diabetes found |
medicalxpress.com |
... number of trial participants, and thickness of line connecting nodes is proportional to number of trial participants randomized in trials directly comparing the two treatments. Numbers represent the number of trials contributing to each treatment comparison . Certainty of the evidence, according to the confidence in network meta-analysis (CINeMA) framework, is included in the forest plot and classified as low, †moderate, and ‡high confidence of evidence. Credit: BMJ ... |
| 3/16/2022 |
Balance checking (using discrete variables) |
stackexchange.com |
Context I'm doing a field intervention, with 4 treatments and 1 control. I have done a stratified randomization beforehand to ensure that demographic characteristics (gender, age, income group) are evenly distributed across my treatment and control cells, i.e., I don't have a scenario where Treatment 1, for instance, is dispatched to all females, which would clearly not be ideal.So this is what my table looks like.What happened I ... |
| 3/1/2022 |
Does One Mab Come Out on Top for Boosting Lung Function in Asthma? |
medpagetoday.com |
PHOENIX -- In some patients with eosinophilic asthma, dupilumab (Dupixent) offered the highest chance of better lung function, although the agent also carried the highest odds of serious adverse events (AEs), a researcher reported.In an indirect treatment comparison of dupilumab, mepolizumab (Nucala), and benralizumab (Fasenra), patients with eosinophil counts ≥300 cells/μL treated with dupilumab had the highest probability of decreased exacerbations and improved pre-bronchodilator lung functioning, according ... |
| 2/24/2022 |
Comparing Biologics for Reducing Severe Asthma Exacerbation Rates |
hmpgloballearningnetwork.com |
Dupilumab was associated with lower rates of severe asthma exacerbations and greater lung function gains than other biologic treatments in patients with uncontrolled persistent asthma, according to an indirect treatment comparison published in Respiratory Medicine.“Currently, five biologic treatment options are available for use in patients with uncontrolled persistent asthma: three interleukin (IL)-5 antagonists, which either bind to the anti-IL-5 ligand (mepolizumab, reslizumab) or to the IL ... |
| 2/23/2022 |
Diabetes: Treatment includes apple cider vinegar |
technocodex.com |
Diabetes: Treatment includes apple cider vinegar Health By Ayub khan On Feb 23, 2022 0 Share (adsbygoogle = window.adsbygoogle []).push(()); The haemoglobin A1c (HbA1c) test tells you your average level of blood sugar over the past two to three months and fasting blood sugar measures your blood sugar after an overnight fast. Informed consent from all patients and ethical approval from the institutional ethics board was obtained. (adsbygoogle = window.adsbygoogle []).push(()); What ... |
| 2/23/2022 |
Diabetes: ‘Two teaspoons’ of a golden liquid shown to lower high blood sugar – ‘effective’ |
timesnewsexpress.com |
The haemoglobin A1c (HbA1c) test tells you your average level of blood sugar over the past two to three months and fasting blood sugar measures your blood sugar after an overnight fast.Informed consent from all patients and ethical approval from the institutional ethics board was obtained.What did the researchers find out?All the parameters underwent a more significant reduction in fasting blood sugar and HbA1c in the apple ... |
| 2/17/2022 |
DOACs Cut Recurrent VTE in Adults With Cancer-Related Thrombosis |
Physicians Weekly |
THURSDAY, Feb. 17, 2022 (HealthDay News) — For adults with cancer-associated thrombosis (CAT), direct oral anticoagulants (DOACs) significantly reduce recurrent venous thromboembolism (VTE) events without increasing major bleeding compared with dalteparin, according to a review published online in the February issue of the Mayo Clinic Proceedings.Irbaz Bin Riaz, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a living, interactive systematic review to examine the benefits ... |
| 2/17/2022 |
DOACs Cut Recurrent VTE in Adults With Cancer-Related Thrombosis |
drugs.com |
DOACs Cut Recurrent VTE in Adults With Cancer-Related ThrombosisTHURSDAY, Feb. 17, 2022 -- For adults with cancer-associated thrombosis (CAT), direct oral anticoagulants (DOACs) significantly reduce recurrent venous thromboembolism (VTE) events without increasing major bleeding compared with dalteparin, according to a review published online in the February issue of the Mayo Clinic Proceedings.Irbaz Bin Riaz, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a living ... |
| 2/17/2022 |
DOACs Cut Recurrent VTE in Adults With Cancer-Related Thrombosis |
healthday.com |
THURSDAY, Feb. 17, 2022 (HealthDay News) -- For adults with cancer-associated thrombosis (CAT), direct oral anticoagulants (DOACs) significantly reduce recurrent venous thromboembolism (VTE) events without increasing major bleeding compared with dalteparin, according to a review published online in the February issue of the Mayo Clinic Proceedings.Irbaz Bin Riaz, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a living, interactive systematic review to examine the benefits and ... |
| 2/17/2022 |
DOACs Cut Recurrent VTE in Adults With Cancer-Related Thrombosis | Health and Fitness | journalstar.com |
journalstar.com |
THURSDAY, Feb. 17, 2022 (HealthDay News) -- For adults with cancer-associated thrombosis (CAT), direct oral anticoagulants (DOACs) significantly reduce recurrent venous thromboembolism (VTE) events without increasing major bleeding compared with dalteparin, according to a review published online in the February issue of the Mayo Clinic Proceedings .Irbaz Bin Riaz, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a living, interactive systematic review to examine the benefits and ... |
| 2/17/2022 |
DOACs Cut Recurrent VTE in Adults With Cancer-Related Thrombosis | Health-med-fit | wiscnews.com |
wiscnews.com |
THURSDAY, Feb. 17, 2022 (HealthDay News) -- For adults with cancer-associated thrombosis (CAT), direct oral anticoagulants (DOACs) significantly reduce recurrent venous thromboembolism (VTE) events without increasing major bleeding compared with dalteparin, according to a review published online in the February issue of the Mayo Clinic Proceedings .Irbaz Bin Riaz, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a living, interactive systematic review to examine the benefits and ... |
| 2/17/2022 |
DOACs Cut Recurrent VTE in Adults With Cancer-Related Thrombosis | State and National News | Maryville Daily Forum |
maryvilleforum.com |
THURSDAY, Feb. 17, 2022 (HealthDay News) -- For adults with cancer-associated thrombosis (CAT), direct oral anticoagulants (DOACs) significantly reduce recurrent venous thromboembolism (VTE) events without increasing major bleeding compared with dalteparin, according to a review published online in the February issue of the Mayo Clinic Proceedings .Irbaz Bin Riaz, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a living, interactive systematic review to examine the benefits and ... |
| 2/17/2022 |
DOACs Cut Recurrent VTE in Adults With Cancer-Related Thrombosis |
madison.com |
THURSDAY, Feb. 17, For adults with cancer-associated thrombosis (CAT), direct oral anticoagulants (DOACs) significantly reduce recurrent venous thromboembolism (VTE) events without increasing major bleeding compared with dalteparin, according to a review published online in the February issue of the Mayo Clinic Proceedings .Irbaz Bin Riaz, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a living, interactive systematic review to examine the benefits and harms of different ... |
| 2/3/2022 |
Funding Available Health Demo Projects |
yankton.net |
... will compensate producers for conducting strip trials of cover crops vs. no cover crops within a diverse crop rotation using no-till planting and other soil health management techniques. Producers will receive $1,800 per treatment comparison unit, up to a maximum of $7,500 per year, to conduct these strip trials, develop case studies, and host field days.For more information on Soil Health Management Demonstration Projects, contact NRCS at the ... |
| 9/29/2021 |
Upwelling-level acidification and pH variability moderate effects of ocean acidification on brain gene expression in black surfperch (Embiotoca jacksoni), a temperate fish with no pelagic larval stage |
news-oceanacidification-icc.org |
... gene expression analysis and gene set enrichment analysis identified significant differential expression of specific genes and gene sets both in comparisons of static pH level treatments as well as in static vs. variable pH treatment comparison s where mean pH was consistent. Enriched gene sets included those related to ion transport, signaling pathways, mRNA processing and splicing, and epigenetic regulation of gene expression, among others. Importantly, we found that pH variability ... |
| 9/21/2021 |
Cost-Effectiveness of Belantamab Mafodotin for MM |
hmpgloballearningnetwork.com |
... for this study used a commercial payer’s perspective over a 10-year time horizon.Efficacy data were based on parametric survival analysis of DREAMM-2 and STORM Part 2, and matching-adjusted indirect treatment comparison between DREAMM-2 and STORM Part 2.Drug treatment, concomitant medications, adverse event management, subsequent treatments, and disease management were considered cost inputs for this study.When compared to selinexor plus dexamethasone, belamaf decreased ... |
| 9/21/2021 |
Computational Scientist |
monster.com |
... gene expression, co-expression analysis, and interrogation of target signatures of interest in cell phenotypes from tissue or circulating immune cells (PBMCs). - Will be expected to apply any needed normalization techniques to perform longitudinal treatment comparison or intra-patient tumor heterogeneity comparisons under scientific supervision. - Need to be well versed in pipelines or R-packages used in single cell expression analysis. - Basic correlation of data outputs with clinical cohort data ... |
| 9/8/2021 |
Matching-adjusted indirect treatment comparison of liso-cel versus axi-cel in relapsed or refractory large B cell lymphoma |
biomedcentral.com |
Research - Open Access - Published:] Matching-adjusted indirect treatment comparison of liso-cel versus axi-cel in relapsed or refractory large B cell lymphoma [Journal of Hematology & Oncology volume 14, Article number: 140 (2021) Cite this article 1 Altmetric - Abstract Background In the absence of randomized studies directly comparing chimeric antigen receptor T cell therapies, this study used matching-adjusted indirect comparisons (MAIC) to evaluate the comparative efficacy and safety ... |
| 9/6/2021 |
EUROMAL 2021 – Biological impacts of ocean warming and acidification on cephalopds: a meta-analysis |
news-oceanacidification-icc.org |
Euromal 2021 – 9th European Congress of Malacological Societies, Prague Date: 5 – 9 September, 2021 Hosted by: Czech University of Life sciences Prague Date: 7 September 2021 Time: 2:35 pm Title: Biological impacts of ocean warming and acidification on cephalopods: a meta-analysis Presenter: Franscisco Borges Description: Cephalopods hold a relevant ecological role in the world’s oceans, being widely known for their cognitive and behavioural prowess. Found in ... |