Pharmacogenomic Analysis

RXVIP Concierge Defends the Critical Role of Pharmacists as Front-Line Healthcare Providers | PR Newswire | 7/1/2020

… an extension of their medical team, RXVIP Concierge staffs them with a healthcare provider who facilitates a high-quality level of care for patients and delivers an unmatched suite of services including: Medication Reconciliations Pharmacogenomic Analysis & PGx Testing Annual Wellness Visits Advanced Care Planning Chronic Care Management Direct Observed Therapy Remote Patient Monitoring Alcohol, Obesity, CVD and other types of counseling RXVIP Concierge is also helping champion federal and state …

MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma | 3/10/2020

… of candidate microRNA signatures and contextualized them in relevant transcriptomic and epigenomic networks. Our results reveal the existence of molecularly defined phenotypes associated with outcome independent of clinicopathologic features. Through machine learning based integrative pharmacogenomic analysis , the microRNA biomarkers identify novel therapeutics for stratified application in osteosarcoma. The previously unrecognized osteosarcoma subtypes with distinct clinical courses and response to therapy could be translatable for discerning patients appropriate for more intensified …

Follow Pharmacogenomic Analysis:    

Pharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers | 11/26/2019

Gynecologic malignancy is one of the leading causes of mortality in female adults worldwide. Comprehensive genomic analysis has revealed a list of molecular aberrations that are essential to tumorigenesis, progression, and metastasis of gynecologic tumors. However, targeting such alterations has frequently led to treatment failures due to underlying genomic complexity and simultaneous activation of various tumor cell survival pathway molecules. A compilation of molecular characterization of tumors with pharmacological drug …

Creating reproducible pharmacogenomic analysis pipelines | Nature | 9/3/2019

Article” lang=”en” Full size table Tracking Data Provenance and Validating Pipeline Integrity Tracking data provenance with CWL can be further enhanced through the use of the provenance flag (–provenance) when executing the PSet workflows 11 . Here, a Research Object is automatically generated, which is a directory that acts as a bundled container for all of the resources utilized and produced within our workflows, including metadata that annotates each resource …