Patient Recruitment

NOXXON Announces That Data Safety Monitoring Board Validates Further NOX-A12 Dose Escalation in Phase 1/2 Brain Cancer Study | 11/9/2020

… a biotechnology company focused on improving cancer treatments by targeting the tumor microenvironment (TME), announced today that an independent Data Safety Monitoring Board (DSMB) has confirmed that it is safe and appropriate to start patient recruitment for the highest planned dose cohort for the Phase 1/2 NOX-A12 plus radiotherapy brain cancer study. The study investigates three dose regimens of NOX-A12 (200, 400 and 600 mg/week), each combined …

NOXXON Announces That Data Safety Monitoring Board Validates Further NOX-A12 Dose Escalation in Phase 1/2 Brain Cancer Study | Business Wire | 11/9/2020

… a biotechnology company focused on improving cancer treatments by targeting the tumor microenvironment (TME), announced today that an independent Data Safety Monitoring Board (DSMB) has confirmed that it is safe and appropriate to start patient recruitment for the highest planned dose cohort for the Phase 1/2 NOX-A12 plus radiotherapy brain cancer study. The study investigates three dose regimens of NOX-A12 (200, 400 and 600 mg/week), each combined …

NIHR: World’s first participants for Novavax phase 3 Covid-19 vaccine trial enroll through NIHR Patient Recruitment Centre #covid19rftlks | Wordpress.com | 10/22/2020

NIHR October 2020 World’s first participants for Novavax phase 3 Covid-19 vaccine trial enroll through NIHR Patient Recruitment Centre The Novavax trial is investigating the safety, efficacy and immunogenicity of NVX-CoV2373. It will recruit up to 10,000 participants aged 18 to 84 years, with and without relevant comorbidities, over the next few weeks from recruitment centres across England. Phase 3 of this trial will focus on the vaccine’s …

First Patient Dosed in Phase 2 Trial to Treat Complications in COVID-19 | 10/22/2020

… acute kidney injury, and other complications caused by inflammation in hospitalized patients with moderate to severe cases of COVID-19. The first patient dosed was at the Broward Health Medical Center in Florida where patient recruitment into the trial continues. Arch will begin screening and recruiting patients next week at clinical sites in Louisiana and in Turkey. The Phase 2 trial is an international, multicenter, randomized, double-blind, placebo-controlled …

Bone Therapeutics reaches 50% treated patients in ongoing JTA-004 Phase III pivotal knee osteoarthritis study Brussels Stock Exchange:BOTHE | Globe Newswire | 10/20/2020

… before year-end. Topline results are anticipated on the 3-month primary endpoint and 6-month follow-up period in the second half of 2021. “ The COVID-19 pandemic has posed major challenges to patient recruitment across the industry. In spite of this, Bone Therapeutics, with the support of NBCD, has been able to treat over 50% of the patients in the JTA-004 Phase III trial in just over …

Bone Therapeutics reaches 50% treated patients in ongoing JTA-004 Phase III pivotal knee osteoarthritis study | Globe Newswire | 10/20/2020

… before year-end. Topline results are anticipated on the 3-month primary endpoint and 6-month follow-up period in the second half of 2021. “ The COVID-19 pandemic has posed major challenges to patient recruitment across the industry. In spite of this, Bone Therapeutics, with the support of NBCD, has been able to treat over 50% of the patients in the JTA-004 Phase III trial in just over …

IQVIA Holdings Inc. (IQV) Q3 2020 Earnings Call Transcript | 10/20/2020

… solutions are proving to be effective workarounds. The pace of startup activity picked up significantly during the third quarter and we are pretty much back to baseline levels for site initiation visits. Of course, patient recruitment trends have started to follow as well. Moving to Technology & Analytics. As expected, TAS has remained resilient throughout this crisis in almost every area. We’ve had very little interruption in data supplier demand. Our …

Global Healthcare Market Outlook 2020 Post-Pandemic - Top Growth Opportunities for Companies to Survive the Remainder of 2020 | PR Newswire | 10/19/2020

… have significant impact and transformation on economies, societies, and lives. Among the considerations: Disrupted clinical trials and the subsequent delay in drug launches will pave the way for fully virtual trials, and hybridization of patient recruitment , retention, and monitoring will become pervasive. An increase in point-of-care testing for infectious diseases is inevitable. With the looming change in service models, alternate testing sites such as pharmacies will become permanent …

Transforming patient recruitment during and after a global pandemic | 10/19/2020

… efficient manner harder to achieve. For the first time we have the data, the technology and the depth of insight to rise to the challenge. A new era of human-centric recruitment For decades, patient recruitment has been a challenge for trial sponsors. Now, in a new era of recruiting that includes recruiting new patients beyond the traditional databases, research shows that 85% of patients are willing to participate in …

PREventive effect of FENestration with and without clipping on post-kidney transplantation lymphatic complications (PREFEN): study protocol for a randomised controlled trial | BMJ | 10/13/2020

Clipping the fenestration edges, (A) without easy flow drain, and (B) with easy flow drain. Patient and public involvement The patients and public were not involved in the planning of this study. Modification of the protocol If any modifications are necessary after patient recruitment starts, the amendments will be submitted to the ethics committee and no further patients will be recruited until the amendments are accepted. Assessment of safety and …

Reify raises $30M in Series B round for clinical trial cloud computing system | MedCity News | 10/12/2020

The company’s software system is designed to streamline the work done by staff at clinical trial sites, such as manually copying information about patient recruitment and enrollment. Post a comment / Aug 12, 2020 at 11:11 AM Shares 0 A company that markets cloud computing systems for the biopharma industry has raised $30 million in a Series B funding round. Boston-based Reify Health said Wednesday that it had closed the …

Immunotherapy Firm Announces Positive Top-Line Trial Results for Severe and Critical COVID-19 Patients | 10/8/2020

… COVID-19 patient population. The Israel-based company’s plan now is to obtain regulatory approval for a larger Phase 2 trial of COVID-19 patients in severe or critical condition. Once approval is received, patient recruitment will start. In other news, Selvaraju reported, Enlivex is preparing and intends to commence a Phase 2b trial of Allocetra in severe sepsis. Should this study get underway before year-end 2020, top-line …

BetterLife Announces VirTrial as Clinical Trial Patient Monitoring Partner | Globe Newswire | 10/8/2020

… test the efficacy of AP-003, a proprietary interferon alpha 2b formulation. VirTrial is a telehealth platform provider that is changing the way pharmaceutical companies conduct clinical trials and enabling research sites to improve patient recruitment and retention. VirTrial’s platform enables BetterLife to empower their selected clinical research sites to perform virtual visits – a combination of secure video, audio, chat and messaging, which can be used on any device. Incorporating …

BetterLife Announces VirTrial as Clinical Trial Patient Monitoring Partner | BioSpace | 10/8/2020

… test the efficacy of AP-003, a proprietary interferon alpha 2b formulation. VirTrial is a telehealth platform provider that is changing the way pharmaceutical companies conduct clinical trials and enabling research sites to improve patient recruitment and retention. VirTrial’s platform enables BetterLife to empower their selected clinical research sites to perform virtual visits – a combination of secure video, audio, chat and messaging, which can be used on any device. Incorporating …

Google Alert - promote | 10/6/2020

… to promote environmental awareness, activism Grand Forks Herald UND law students to host Wild & Scenic Film Festival to promote environmental awareness, activism. Written By: Pamela D. Knudson Oct 6th 2020 … Flag as irrelevant Trialbee Patient Recruitment Services Selected to Promote Patient Diversity for Leading COVID-19 … BioSpace Trialbee Patient Recruitment Services Selected to Promote Patient Diversity for Leading COVID-19 Vaccine Trials. Published: Oct 06, 2020. MALMÖ … Flag as irrelevant …

Half-year report | 9/24/2020

… HIGHLIGHTS Clevegen ® ( bexmarilimab ) - Regulator of major inhibitory immune checkpoints and wholly-owned novel cancer immunotherapy in development Clinical Development Updates: Dosing of Part II of the ongoing MATINS trial commenced in February, with strong patient recruitment across 10 cancer types (ER-positive breast cancer, cholangiocarcinoma (bile duct cancer) and gall bladder cancer, colorectal cancer, gastric cancer, hepatocellular carcinoma, cutaneous melanoma, uveal melanoma, ovarian cancer, pancreatic ductal adenocarcinoma and anaplastic thyroid …

Biorasi Commended by Frost & Sullivan for its Full-service Offering to Drive Rare Disease Patient Recruitment for CROs | PR Newswire | 9/22/2020

… analysis of the North American contract research organization (CRO) market, Frost & Sullivan recognizes Biorasi, LLC with the 2020 North American Entrepreneurial Company of the Year Award. Biorasi’s milestone-based, patient-centric approach to driving patient recruitment for rare diseases, hard-to-recruit indications, and clinical trial rescues differentiate it from its peers. Its special expertise in neurology, nephrology, dermatology, and oncology as well as relationships with global site networks across …

COVID-19 clinical trials: learning from exceptions in the research chaos | Nature | 9/22/2020

… to assess the effect of remdesivir on time to disease resolution 3 . The speed of the RECOVERY trial ( https://www.recoverytrial.net/files/recovery-protocol-v7-0-2020-06-18.pdf ) was record-breaking: the period from protocol to first patient recruitment was nine days, with the 176 UK hospitals recruiting 12,000 hospitalized patients (15% UK COVID-19 cases), and it provided clear answers within a few months on the effectiveness of dexamethasone 2 and the …

PRA Health Sciences and Deep Lens announce strategic relationship to accelerate patient recruitment for precision cancer trials | BioSpace | 9/18/2020

PRA Health Sciences and Deep Lens announce strategic relationship to accelerate patient recruitment for precision cancer trials Published: Sep 18, 2020 The two companies bring together cloud-based mobile technologies to improve the identification, screening and matching of patients to precision-based clinical oncology trials RALEIGH, N.C. and COLUMBUS, Ohio, Sept. 18, 2020 (GLOBE NEWSWIRE) – PRA Health Sciences, Inc. (NASDAQ: PRAH) and Deep Lens, Inc. , announced today a new strategic …

Research Manager Band 6 | 9/17/2020

… of the recently launched St George’s NHS Trust 2019 -24 research strategy. St George’s NHS Trust has enjoyed much success in improving our research performance in recent years. We have more than doubled our patient recruitment to clinical research studies and recruited 13,000 patients across 274 studies in the year 2018/19. More recently, we have been successful in undertaking Covid clinical research, and are amongst the top in the country …

Patient recruitment starts for the international PRO-SID study evaluating Panzyga® for primary prophylaxis in patients with chronic lymphocytic leukaemia and secondary immunodeficiency | BioSpace | 9/17/2020

Secondary immunodeficiency (SID) is a common complication in patients with haematological malignancies such as CLL. Up to 85% of CLL patients develop hypogammaglobulinemia during the course of the disease, either due to the underlying disease or as a side effect of their treatment. 1 For example, in one study, 39% of CLL patients developed hypogammaglobulinaemia after treatment with a B-cell depleting therapy. 2 Patients with hypogammaglobulinaemia are more likely …

Coronavirus tracker: Pfizer unveils trial protocol for vaccine; Treasurers ask Gilead to lower remdesivir price | FiercePharma | 9/17/2020

After Moderna unveiled its vaccine’s phase 3 trial protocol, Pfizer followed suit Thursday afternoon. Plus, a group of state treasurers asked Gilead to reconsider its price for remdesivir. And CDC director Robert Redfield tempered hopes of a quick nationwide launch. The worldwide case count passed 29.8 million Thursday morning, with more than 941,000 reported deaths, according to Johns Hopkins University’s COVID-19 dashboard . Please read below for the latest updates …

Silence Therapeutics PLC (SLN) Q2 2020 Earnings Call Transcript | 9/15/2020

… remain fully committed to continuing the development of our clinical pipeline, but we have to acknowledge the timelines of the clinical programs or data readouts could be impacted by future COVID related restrictions on patient recruitment at the clinical trial sites. As we sit here at the moment, we are very confident that we can move forward and obviously Giles Campion will give you a little bit more flesh on …

Getting Started With Patient-Centric Solutions in Your Organization | 9/10/2020

… partnership that benefits both companies and patients. As mentioned in the previous blog , incorporating a patient centricity by design framework through the lifecycle of the drug development process has many advantages, from improvements in patient recruitment and retention, better trial outcomes, lower costs, and shorter timelines. But how do companies go about becoming more patient centric? Japan-based pharmaceutical giant Takeda provides a good example. Starting in 2018, the company …

New Study Published in PLOS Medicine Explores Impact of Race, Age & Comorbidities on COVID-19 Mortality | PR Newswire | 9/10/2020

… data to make clinical and observational research easier and more efficient. TriNetX combines real time access to longitudinal clinical data with state-of-the-art analytics to optimize protocol design and feasibility, site selection, patient recruitment , and enable discoveries through the generation of real-world evidence. The TriNetX platform is HIPAA and GDPR compliant. For more information, visit TriNetX at www.trinetx.com or follow @TriNetX on Twitter. Media Contact: TriNetX Jennifer …