Gut Microbiome

How Environmental Toxins and Glyphosate Damage the Thyroid | 8/11/2020

… the master hormone gland, is suppressed, this can result in low TSH (114) (115). Researchers state that more studies are needed on the effects of glyphosate on the thyroid as well as on the gut microbiome , which could also impact genetic and thyroid function. How Carbamates Reduce Thyroid Function Carbamates work similarly to organophosphates on the nervous system and are widely used in agriculture as insecticides, herbicides, and fungicides (116 …

All About the Skin Microbiome (And 5 Ways to Keep it in Balance) | 8/10/2020

… that it deserves. Recommended Reading: 5 Little Known Natural Skin Care Ingredients That Will be Mainstream in 5 Years get acquainted with your microbiome You may already be familiar with its close relative, the gut microbiome , because the wellness movement has been steadily educating the public on how gut health affects the body. We have been learning that our bodies are ecosystems that harbor a microbial universe and within that …

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How to Heal Your Gut Naturally with Lee Holmes | 8/10/2020

… simple Spit Test! What is an unhealthy gut? If you’ve been suffering from high stress, not enough sleep, maybe eating too much sugary food, overdosing on processed foods, or perhaps taking antibiotics then your gut microbiome could be in a bad way. Some signs of an unhealthy gut could include: Upset Stomach Auto immune problems Lee’s Healthy Gut Health tips As a Holistic Food and Nutrition Coach, whole foods chef …

The “”Staggered mix 2″” sample was amplified with a different pol | 8/10/2020

… proportions inferred from 454 GS FLX sequence data (y-axis). Discussion Many studies have linked the composition and dynamics of the human microbiome with health and disease. Because of the immense differences in the gut microbiome among individuals, large sample sizes are often needed click here to correlate microbiome composition with biological variables such as disease states [4, 5, 7, 27, 38]. We have thus conducted a detailed investigation of …

How to boost your metabolism naturally: seven workout and diet tips from HIIT and better sleep to spicy food | MSN | 8/10/2020

… from vegetables, fish, lean meat etc as the natural sources contain other beneficial substances as well, not just synthesised vitamins found in food supplements. Probiotics can also help improve metabolism and maintain a healthy gut microbiome , essential for well-functioning digestion. In a research paper published in 2013, the researchers concluded that “Probiotics may restore the composition of the gut microbiome and introduce beneficial functions to gut microbial communities, resulting …

Identifying mechanisms that predict weight trajectory after bariatric surgery: rationale and design of the… | National Institutes of Health | 8/10/2020

… anatomic and physiologic alterations that lead to changes in behavior and biology. Unfortunately, many patients experience suboptimal weight loss and/or substantial weight regain. Eating and physical activity/sedentary behaviors, mood, cognition, and the gut microbiome all change postoperatively and have an association with weight change. The longitudinal relationship between changes in the gut microbiome and postoperative weight trajectory has not been explored thoroughly, and the interactive associations among the …

Cross-talk between airway and gut microbiome links to IgE responses to house dust mites in childhood airway allergies | National Institutes of Health | 8/10/2020

… for prevention or treatment of allergies. This study aimed to determine the airway and gut microbial profiles in children with airway allergies using 16S rRNA sequencing. The existence of the association between airway and gut microbiome and its implications in mediating HDM-specific IgE responses for childhood allergic rhinitis and asthma were also examined. Results Population characteristics A total of sixty subjects were enrolled into this study, including 38 children …

Could Huntington’s Disease be Treated Using Gut Bacteria? | 8/9/2020

The gut microbiome , the community of microbes that helps us digest food and absorb nutrients, has been shown to have an influence on many aspects of health and disease. The trillions of microbes that reside in and on our bodies all carry their own genes and can release their own molecules. Scientists are starting to learn more about how specific strains of microbes are connected to certain illnesses, and how …

I’m a Gastroenterologist, and Here’s Why ‘Nutritional Momentum’ Is so Important for Gut Health | MSN | 8/9/2020

… how to use nutritional momentum to benefit gut health. You ready for it? His number one tip is to eat a wide range of plant-based foods. “The single greatest predictor of a healthy gut microbiome is the diversity of plants in your diet ,” he says. Why? Well, Dr. Bulsiewicz says that a diet rich in a variety of different plants (vegetables, fruits, herbs, etc.) primes the microbiome to produce …

Futureseek Daily Link Review; 8 August 2020 | 8/8/2020

… About It VMware gets into apps with Bluetooth-pinging COVID-safe-office tools Offline Translation Earbuds Translate Up To 40 Languages And 93 Accents In Real-Time A new tool for modeling the human gut microbiome AI Could Help Enable Accurate Remote Monitoring of Parkinson’s Patients Engadget Podcast: Diving into everything Samsung (and the Pixel 4a) Scientists May Be Using the Wrong Cells to Study Covid-19 Software that monitors …

24 hour GREEK yogurt recipe ✳️ MAKE YOUR TUMMY HAPPY! (healthy probiotic food for the whole family!) | 8/8/2020

24 hour GREEK yogurt recipe ✳️ MAKE YOUR TUMMY HAPPY! (healthy probiotic food for the whole family!) By Make this healthy homemade yogurt to build up your gut microbiome and take steps to getting your gut health back on track! (affiliated links) 👉🏻 Check out my favorite items on my Amazon Store! https://www.amazon.com/shop/njfamily laptop for video editing: https://geni.us/T8uY3AD voice over microphone: https://geni.us/UuLhBnT wall …

Role of probiotics in patients with colorectal cancer: a systematic review protocol of randomised controlled trial studies | BMJ | 8/8/2020

… in the management and treatment of diarrhoea associated to anti-cancer chemotherapy revolves around the restoration to normal of the intestinal microbiota. 18 The favourable altreation by probiotic bacteria in the makeup of the gut microbiome is closely associated with the reduced risk of suffering from CRC in the future. 19 Production of short chain fatty acids by probiotics which leads to cell apoptosis is one of the aways through …

Gut Bacteria To Be A Potential Drug Target in Huntington’s Patients | 8/7/2020

by Ramya Rachamanti on August 7, 2020 at 4:05 PM Drug News Gut microbiome plays a vital role in patients with Huntington’s disease. Some of the gut measures are associated with disease symptoms, such as impaired movements and thinking. The findings, published in Brain Communications , raise interesting questions regarding the role of the gut in Huntington’s Disease, and its potential as a target for future therapeutic intervention, or for tracking …

A New Tool For Modeling The Human Gut Microbiome | 8/7/2020

A New Tool For Modeling The Human Gut Microbiome Details Share This Several thousand strains of bacteria live in the human gut. Several thousand strains of bacteria live in the human gut. Some of these are associated with disease, while others have beneficial effects on human health. Figuring out the precise role of each of these bacteria can be difficult, because many of them can’t be grown in lab studies …

6 health benefits of fiber and how to add more to your diet | MSN | 8/7/2020

… folate and puts them to work in your bloodstream. Researchers are just beginning to understand all that these hungry bacteria do. But a 2011 paper published in Surgical Clinics of North America found the gut microbiome supports metabolism, contributes to your immune system, regulates energy levels, and much more. Prebiotic foods are especially beneficial for gut health. These foods, like onions and garlic, contain “fermented fiber.” As the bacteria in …

Seaweed extract supports immune function in athletes, Australian study finds | 8/7/2020

… the seaweed extract fucoidan to improve the gut health of high performance athletes. Fucoidan is a highly bioactive compound found naturally in brown seaweeds. Independent research supports the beneficial effects of fucoidan on both gut microbiome and the immune system. These areas are of particular interest to elite athletes whose intense and prolonged exercise regimes often exacerbate inflammation in the gut and destabilise the microbiome. The new study was led …

Now You Can Use Cutting Edge AI to Take Control of Your Cellular and Gut Health | 8/6/2020

Share via Email Partnerships Now You Can Use Cutting Edge AI to Take Control of Your Cellular and Gut Health Viome’s Gut Intelligence and Health Intelligence Services give you the most personalized dietary and nutritional recommendations possible. / Gut Microbiome We all know that what we eat affects our health. We know eating foods that are high in fat can lead to weight gain and obesity. We know eating too much …

Blueberry-enriched diet may help women’s muscle growth, repair: Study | 8/6/2020

Research on the role that blueberries may play in promoting good health is ongoing across multiple areas, including cardiovascular health, diabetes management, brain health, exercise and the gut microbiome . health Updated: Aug 06, 2020 08:26 IST Asian News International  Posted by Saumya Sharma California [US] This study is an important step in translating findings from cell culture and rodent studies to a potential dietary therapy for improving muscle regeneration after …

Gut Microbiome Influences B Cell and Antibody Repertoire | 8/6/2020

… to avoid the dangers of sepsis. It also shows that different B cell immune strategies in different body compartments are important for the maintenance of our peaceful existence with our microbial passengers. The post Gut Microbiome Influences B Cell and Antibody Repertoire appeared first on GEN - Genetic Engineering and Biotechnology News …

Using the Wisdom of Nutritional Psychiatry to Combat Anxiety | 8/6/2020

Untangling the relationship between the gut and mental health is a bit like trying to sort out if the chicken came before the egg, says nutritional psychiatrist Uma Naidoo. “In my practice, I often see people after a referral and then help them correct how they eat to improve their gut microbiome and, ultimately, improve mental health symptoms,” Naidoo says. “But we need to envision the gut-brain axis as …

BioSpace Global Roundup, Aug. 6 | 8/6/2020

… for immunotherapy. Enterome – France-based Enterome SA published a new study in Nature Biotechnology describing the creation of the most comprehensive and unified catalog to-date of genomic and proteomic data from the human gut microbiome . These reference catalogs build on previous global projects aimed at characterizing the human gut microbiome , such as the Human Microbiome Project. The goal of this research is to enable a better understanding of the …

Gut bacteria in people with Huntington’s disease may be a potential drug target | 8/6/2020

A world first clinical study of the gut microbiome in people with Huntington’s disease (HD) has found that it is not just a disease of the brain, but also of the body. The study, led by Monash University’s Turner Institute for Brain and Mental Health, with collaboration from the Florey Institute for Neurosciences found evidence of gut dysbiosis (altered bacteria in the gastrointestinal tract) in people with HD, with some …

The Gut Microbiome Helps Determine B Cell and Antibody Repertoire | 8/6/2020

… avoid the dangers of sepsis. It also shows that different B cell immune strategies in different body compartments are important for the maintenance of our peaceful existence with our microbial passengers. The post The Gut Microbiome Helps Determine B Cell and Antibody Repertoire appeared first on Clinical OMICs - Molecular Diagnostics in Precision Medicine …

Superfood Mushrooms to Boost Brain Health - CATALOG MAGAZINE | 8/6/2020

… that boost nerves in the brain, regular consumption of mushrooms can help ward off the development of dementia. Additionally, the shrooms also serve other health-boosting functions like—boosting immunity, fighting cancer cells, enhancing gut microbiome , enhancing energy and libido, and controlling blood sugar. They were an integral part of the traditional Chinese medicine and the Ayurveda system of medicine for long, till the so-called “modern” people incorporated these …

Study finds evidence of gut dysbiosis in people with Huntington’s disease | 8/6/2020

Exploring how bacteria and viruses coexist inside the human gut The lead researchers, Neuropsychology Doctoral Candidate Cory Wasser and Professor Julie Stout, Director of Monash University’s Clinical Cognitive Neuroscience Laboratory, used fecal samples to investigate whether the gut microbiome in people with HD differs to those without the HD gene. The study included 42 participants with the HD gene, including 19 people with HD, 23 people with the HD gene …

Tufts University

Summit Announces Publication of Phase 2 Clinical Analyses of Gut Microbiome Health | Globe Newswire | 7/13/2020

Gut Microbiome Health Oxford, UK, and Cambridge, MA, US, July 13, 2020 – Summit Therapeutics plc (NASDAQ: SMMT) today announces the publication of data from the Phase 2 clinical trial of the company’s precision antibiotic, ridinilazole, in development for the treatment of C. difficile infection (‘CDI’) in the American Journal of Physiology – Gastrointestinal and Liver Physiology . The data published in collaboration with researchers at Tufts University and Tufts Medical Center demonstrated …

Clinical Research

Symbiotic bacteria enhance exercise performance | BMJ | 5/23/2020

Symbiotic bacteria enhance exercise performance http://orcid.org/0000-0002-0174-5210 Jon O Lundberg 1 , 1 Physiology and Pharmacology , Karolinska Institutet , Stockholm , Sweden 2 NIHR Exeter Clinical Research Facility, University of Exeter Medical School , Exeter , UK Correspondence to Dr Jon O Lundberg, Physiology and Pharmacology, Karolinska Institutet, Stockholm 171 65, Sweden; jon.lundberg{at}ki.se exercise physiology In a recent Nature Medicine article Scheiman and colleagues studied the influence of the gut microbiome on …

COVID-19

Synthetic Biologics Reports 2020 First Quarter Operational Highlights and Financial Results | PR Newswire | 5/5/2020

… GI and microbiome-focused clinical development programs while responding to the unprecedented global health and economic crisis sparked by the COVID-19 pandemic,” said Steven A. Shallcross , Chief Executive and Financial Officer of Synthetic Biologics … to reduce the impact of methane-producing organisms in the gut microbiome to treat an underlying cause of irritable bowel syndrome with constipation (IBS-C). The Company is also advancing SYN-020, an oral formulation …

Ohio State University

Danone North America Awards $50,000 in Student Grants to Further Yogurt and Gut Microbiome Exploration | PR Newswire | 4/28/2020

WHITE PLAINS, N.Y. and BROOMFIELD, Colo. , April 28, For the eighth year in a row, Danone North America has demonstrated their commitment to science and education through the Danone Gut Microbiome, Yogurt and Probiotics Fellowship Grant Program. This year’s honorees are Erica Kosmerl of The Ohio State University and Elizabeth Morrison of Indiana University . A committee of nutrition scientists selected the two winners based on the quality of their proposals …

Food and Drug Administration

Applied BioCode Releases SARS-CoV-2 Assay with High Throughput BioCode® MDx-3000 System | Business Wire | 4/24/2020

… in an 8 hour shift) to help address the testing needs. Applied BioCode has submitted the notification to the U.S. Food and Drug Administration (FDA) for release of the test under Emergency Use Authorization (EUA … with applications that include the infectious disease, autoimmune disease, allergy, gut microbiome, and veterinary markets. Contacts Applied BioCode Dr. Winston Z. Ho President +1 (562) 777-9800 …

CDC

Applied BioCode Releases SARS-CoV-2 Assay with High Throughput BioCode® MDx-3000 System | Business Wire | 4/24/2020

… results by detecting two different regions of the SARS-CoV-2 virus N gene which are also utilized by the CDC EUA assay. The assay can be run as an independent assay or in parallel … with applications that include the infectious disease, autoimmune disease, allergy, gut microbiome, and veterinary markets. Contacts Applied BioCode Dr. Winston Z. Ho President +1 (562) 777-9800 …

National Institutes of Health

‘Dead’ Probiotic Bacteria Could Help Ease Irritable Bowel - U.S. News & World Report | 4/9/2020

… more practical to use. IBS is a digestive disorder that affects an estimated 12% of Americans, according to the U.S. National Institutes of Health. It’s thought to be caused by problems in gut-brain communication … show that patients often have a “clear change” in their gut microbiome, according to Dr. Elena Ivanina, a gastroenterologist at Lenox Hill Hospital in New York City. The gut microbiome refers to the trillions of …

Mental Health

COVID-19 Created Stress & Dietary Habits | 4/1/2020

… The study of neurochemistry has revealed a wide variety of new signaling molecules that allow a series of communications from gut microbiome-brain pathways having direct effects on our brain. When combined with heightened levels … off-limits if our goal is to better manage our mental health. The foods we elect to eat can and do result in differences in our state of mental health when processed foods are compared …

Population Health

Drug used for liver disease also affects C. diff life cycle, reduces inflammation in mice | 3/30/2020

gut microbiome and can lead to relapse, or to fecal transplants that may have unknown side effects,” says Casey Theriot, assistant professor of population health and pathobiology at NC State and corresponding author of the work. Theriot and a team of researchers from NC State, Pennsylvania State University and the University of North Carolina at Chapel Hill looked at UDCA treatment of C. diff in vitro and as a pre …

Digital Health

Biotech innovations to spur next phase of personalized care | Modern Healthcare | 3/28/2020

… it in 10 years time,” Bracken said. “There’s so much promise there.” One of the first therapies to leverage the gut microbiome is fecal microbiota transplantation, or stool transplants, to treat Clostridium difficile infections. While … to a 2019 report from the Stanford Medicine Center for Digital Health and early-stage digital health venture fund Rock Health. While most of those devices track more general exercise, sleep and heart rate, and …

NIH

Artificial microbiome heterogeneity spurs six practical action themes and examples to increase study power-driven reproducibility | Nature | 3/19/2020

… analysis for study power-based sample size estimations using preclinical mouse data to support translational clinical trials, as requested in NIH/similar grants or publications. Download PDF Introduction According to a U.S. National Science Foundation … in current literature To identify husbandry factors capable of influencing gut microbiome and study reproducibility, especially mice per cage (MxCg) and mice per group (MxGr), we reviewed 172 recent studies selected from PubMed searching ‘diet …

Human Microbiome

Major Infant Health Collaboration Announced by APC Microbiome Ireland with DuPont Nutrition & Biosciences | PRWeb | 3/13/2020

… with APC with the help of funding from Science Foundation Ireland on solutions and products that are key to our human microbiome platform. By working with the world’s leading microbiome research institute in APC, we … a key role in human health. Establishment of a healthy gut microbiome in early life is influenced by birth mode, antibiotic use and nutrition, including breast milk components. Infant gut microbiota can be severely depleted …

Medical Research

Infant TB Infection Prevention Study (iTIPS): a randomised trial protocol evaluating isoniazid to prevent M. tuberculosis infection in HIV-exposed uninfected children | BMJ | 1/22/2020

… non-blinded to enable prompt clinical management for any potential drug-related adverse event. IGRAs are performed in the Kenya Medical Research Institute (KEMRI) Centers for Disease Control (CDC) laboratory, which is blinded to arm … 41 Infant rectal swabs are collected at enrolment for future gut microbiome studies. Maternal breast milk and blood for PBMC and plasma separation are collected on enrolment. Study procedures specific to infants randomised to INH …

Precision Medicine

Pendulum Therapeutics Announces Formation of Scientific and Medical Advisory Boards | Globe Newswire | 1/21/2020

… from analyzing and deciphering the complex world of the microbiome through rigorous excellent DNA science,” said Eric Schadt, dean for Precision Medicine at the Icahn School of Medicine at Mount Sinai, and founder and CEO … Mouse Core Facility, where he studies the impact of the gut microbiome on nutrition and drug metabolism. Marion Leclerc , PhD, of the French National Institute for Agricultural Research, is an expert in microbial ecology and …

Genomics

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas | Nature | 1/13/2020

… gut microbiome). Cohort acknowledgements, ERF: we are grateful to all study participants and their relatives, general practitioners and neurologists for their contributions and to P. Veraart for her help in genealogy, J. Vergeer for supervision of the laboratory work and P. Snijders for his help in data collection. ERF was supported by the Consortium for Systems Biology (NCSB), both within the framework of the Netherlands Genomics Initiative (NGI)/NWO). The …

Department of Health and Human Services

Danone North America Announces 2019-2020 Gut Microbiome, Yogurt and Probiotics Fellowship Grant | PR Newswire | 12/16/2019

… in a row. As the name indicates, the grant is designed for graduate students to study the role of the gut microbiome, yogurt and probiotics for human health. Scientists in the field have found that … of Common Fund’s Human Microbiome Project (HMP) by the U.S. Department of Health and Human Services in 2007. While there is a better understanding of what a “normal” human microbiome looks like, how its controlled …

American College of Rheumatology

Unmet need in rheumatology: reports from the Targeted Therapies meeting 2019 | BMJ | 12/16/2019

… produced from this meeting. 1 However, with the expanse of targeted therapies and the recent clinical recommendations published from both American College of Rheumatology and the European Union League Against Rheumatism, 2–4 a document … microbiome is paramount. While it is highly likely that the gut microbiome is contributing to the disease, we do not know which bacteria are most important, which portion of the bowel is most important, the …

Clinical Data

Gut uropathogen abundance is a risk factor for development of bacteriuria and urinary tract infection | Nature | 12/4/2019

… these dysbiotic states with pathogenic bacteria can lead to infectious complications beyond C. difficile infection. Taur et al. investigated the gut microbiome profiles of 94 bone marrow transplant recipients and reported that elevated gut Enterococcus … Data availability All sequencing data as well as the deidentified clinical data that support the findings of this study have been uploaded to the database of Genotypes and Phenotypes (dbGaP) with accession number phs001879.v1 …

Brain Health

Can You Eat to Beat Depression? | WebMD | 12/2/2019

… research, scientists aren’t sure how your diet affects your mental health. But they’re zeroing in on one promising area: your gut microbiome . “Of the more than 20 studies we are currently running at the Food … treat depression and may be important for other aspects of brain health, such as dementia . This is true for people across the lifespan – even very young children.” And if you do decide to adjust your …

CRISPR

Rejuvenation Roundup November 2019 | 12/2/2019

… rejuvenation world, with plenty of ups and downs along with twists and turns. Progress in the field continues apace, as CRISPR is in Phase 1 human clinical trials and researchers have reported success with removing … to Combat Cognitive Decline : A recent paper explores modifying the gut microbiome to increase production of butyrate and brain-derived neurotrophic factor (BDNF) in order to aid the brain and fight against age-related cognitive …

Biotech

Monthly Research Review – November 2019 | 12/1/2019

… of Parkinson’s news 1. Alpha Synuclein Antisense A manuscript was posted on the OPEN ACCESS preprint database BioRxiv by the biotech firms ionis Pharma & Biogen and researchers from Michigan State University, which demonstrates antisense oligonucleotides … oh & the researchers observed cell-to-cell transmission! ). 6. PD Gut microbiome points towards bile acids Researchers conducted longitudinal metabolome analysis on 30 drug-naive, de novo Parkinson’s patients (& 30 matched controls) and revealed PD …

RNA Sequencing

Microbiome Sequencing Services Markets, Forecast to 2024 - Surge in Genomic Research and Widening Application Areas of Microbiome Sequencing is Driving the Market | PR Newswire | 11/29/2019

… various biological sectors is spurring the growth of the market. Additionally, many companies are concentrating on novel exome sequencing and RNA sequencing applications in niche market segments. However, despite increased access and reduced cost of … may also contain information about both, the composition of the gut microbiome over time in these patients, as well as the small molecules and proteins being produced by these microbes. North America Dominates the Market …

Personalized Nutrition

Nestlé partners with California school on microbiome research | 11/26/2019

… is to increase the development of nutritional solutions that promote health and well-being. Nestlé noted it has been studying gut microbiome evolution from birth to aging in both humans and pets for several years … rather than the mass market. Developing more functional ingredients for personalized nutrition could not only benefit global CPG firms, but it might result in better ways to manage food allergies, obesity, inflammatory bowel disease and …

American Diabetes Association

Metagenomics and Faecal Metabolomics Integrative Analysis towards the Impaired Glucose Regulation and Type 2 Diabetes in Uyghur-Related Omics | 11/18/2019

… of the important environmental risk factors for metabolic disease [ 5 ] and is associated with biological metabolic markers [ 6 ]. However, the gut microbiome of Chinese Uyghur has not been well explored. Some studies have shown that … twenty subjects were newly diagnosed with T2DM according to the American Diabetes Association (ADA) 2014 criteria. Twenty subjects were grouped in newly diagnosed IGR. The control group comprised 20 normal glucose tolerance (NGT) subjects who …

Smoking Cessation

Quitting smoking could lead to major changes in gut bacteria | 11/18/2019

smoking cessation changes the gut microbiota , and I think that’s a significant piece of science,” said the study’s lead author, Dr. Marcus Sublette. “It’s already been established that smoking changes the gut microbiome. What we’re adding here is that smoking cessation itself will continue to change the gut microbiome. Then the question of course is, “Is this good? Or is it bad?” We don’t know yet.” The study showed improvements …

Novartis

Ex-GSK Shingrix chief Guillaume Pfefer lands at Flagship as its second CEO-partner | FierceBiotech | 7/17/2020

… Afeyan, as well as the hybrid CEO-Partner role. It’s a relatively new position—Flagship picked its first CEO-Partner, Novartis alum Fabrice Chouraqui, in May this year. RELATED: Ex-GSK immunology chief to lead … an adviser. RELATED: Kintai’s obesity drug that works via the gut microbiome moves closer to the clinic One of its leading programs targets the gut microbiome to treat obesity. In January this year, the company …

HealthDay

Can Probiotics Help Ease Depression? | WebMD | 7/9/2020

Can Probiotics Help Ease Depression? By Amy Norton HealthDay Reporter WEDNESDAY, July 8, Probiotic supplements might help ease depression symptoms in some people, a new research review suggests. Researchers found that across seven small clinical … vast array of bacteria and other microbes – known as the “gut microbiome.” And those organisms are believed to do more than just aid in digestion. Research suggests the microbes are involved in everything from immune …

Vedanta Biosciences

Vedanta Biosciences Announces Positive Topline Data from Two Phase 1 Studies of VE202, a Rationally Defined Bacterial Consortium Being Advanced for Inflammatory Bowel Diseases (IBD) | Business Wire | 6/9/2020

CAMBRIDGE, Mass.–( BUSINESS WIRE )– Vedanta Biosciences , a clinical-stage company developing a new category of therapies for immune-mediated diseases based on rationally-defined consortia of human microbiome-derived bacteria, today announced positive topline data … intended effect of robustly and durably colonizing and changing the gut microbiome composition in a targeted manner,” said Bernat Olle, Ph.D., chief executive officer of Vedanta Biosciences. “Current treatments for IBD block mediators of inflammation …

Rebiotix

Rebiotix and Ferring Announce World’s First With Positive Preliminary Pivotal Phase 3 Data for Investigational Microbiome-based Therapy RBX2660 | Business & Finance | heraldchronicle.com | Business Wire | 5/6/2020

… more than ever, the world needs trustworthy reporting—but good journalism isn’t free. Please support us by subscribing. Subscribe AP Rebiotix and Ferring Announce World’s First With Positive Preliminary Pivotal Phase 3 Data for Investigational … 4,5 As a live biotherapeutic, aiming to help restore the gut microbiome community, RBX2660 may bring an innovative therapeutic option to patients suffering from this potentially deadly infection. “C. diff infection is a significant public …

Johnson & Johnson

Evolve BioSystems, Inc. Announces Collaboration with Janssen to Study the Impact of B. infantis EVC001 in the Reduction of Atopic Dermatitis | PR Newswire | 3/26/2020

DAVIS, Calif. , March 26, Evolve BioSystems, Inc., a global leader dedicated to improving human health through the gut microbiome, today announced a collaboration with Janssen Research & Development, LLC, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, to conduct a clinical study in children at risk for developing atopic dermatitis. The study will assess the effects of introducing a specific gut bacterium, Bifidobacterium longum subspecies infantis (activated B. infantis EVC001 …

uBiome

Pharmacomicrobiomics in inflammatory arthritis: gut microbiome as modulator of therapeutic response | Nature | 3/10/2020

… and diagnostic methods relating to rheumatoid arthritis”). P.J.T. declares he is on the scientific advisory boards for Kaleido, Seres, SNIPRbiome, uBiome, and WholeBiome; there is no direct overlap between the current article and these consulting … Nayak, R.R., Ubeda, C. et al. Pharmacomicrobiomics in inflammatory arthritis: gut microbiome as modulator of therapeutic response. Nat Rev Rheumatol (2020). https://doi.org/10.1038/s41584-020-0395-3 …

Viome

Want Better Gut Health? Start With an Advanced Gut Microbiome Test. | 2/27/2020

Want Better Gut Health? Start With an Advanced Gut Microbiome Test. Viome uses cutting edge science to map out every organism in your gut. / Microbiome Futurism fans: To create this content, a non-editorial team worked with an affiliate partner. We may collect a small commission on items purchased through this page. This post does not necessarily reflect the views or the endorsement of the Futurism.com editorial staff. Are you …

Apple Health

Physician and New York Times Bestselling Author Dr. Michael Greger Officially Releases New Sustainable Weight Loss Book - HOW NOT TO DIET | PR Newswire | 12/10/2019

Apple Books , and Barnes & Noble . The book just officially released on December 10, 2019 . Dr. Greger has honed in on the optimal criteria to enable weight loss while considering how these foods actually affect health and longevity. The book lays out the key ingredients of the ideal weight-loss diet—factors such as calorie density, the insulin index, and the impact of foods on the gut microbiome—showing how plant …

Qiagen

Gut uropathogen abundance is a risk factor for development of bacteriuria and urinary tract infection | Nature | 12/4/2019

… these dysbiotic states with pathogenic bacteria can lead to infectious complications beyond C. difficile infection. Taur et al. investigated the gut microbiome profiles of 94 bone marrow transplant recipients and reported that elevated gut Enterococcus … The DNA was further purified using QIAamp mini spin columns (Qiagen, Hilden, Germany). For each sample, duplicate 50 μL PCR reactions were performed, each containing 50 ng of purified DNA, 0.2 mM dNTPs, 1.5 mM …

Biogen

Monthly Research Review – November 2019 | 12/1/2019

… Alpha Synuclein Antisense A manuscript was posted on the OPEN ACCESS preprint database BioRxiv by the biotech firms ionis Pharma & Biogen and researchers from Michigan State University, which demonstrates antisense oligonucleotides targeting alpha synuclein mRNA … oh & the researchers observed cell-to-cell transmission! ). 6. PD Gut microbiome points towards bile acids Researchers conducted longitudinal metabolome analysis on 30 drug-naive, de novo Parkinson’s patients (& 30 matched controls) and revealed PD …

Arivale

How Old Are You? Your Body Might Disagree With That Answer | PRWeb | 11/23/2019

… may be improved.” The study sampled men and women who varied by age and health status and who participated in Arivale (now closed), which was a consumer data-intensive “scientific wellness” program. The wellness program … ISB findings, notably that the alpha diversity of an individual’s gut microbiome can be accurately predicted by examining metabolites in the blood, and that combining personal, dense, dynamic data (PD3) clouds with tailored behavioral coaching …

Thermo Fisher

Blueberry Attenuates Liver Fibrosis, Protects Intestinal Epithelial Barrier, and Maintains Gut Microbiota Homeostasis | 11/22/2019

… was monitored by ALT and AST activity, protein and mRNA were determined by western blot and RT-qPCR, and the gut microbiome was detected by Miseq. Results . The results showed that blueberry could reduce the … on an ABI 7900 Real-Time PCR system (Applied Biosystems; Thermo Fisher Scientific, Inc.). The following primer pairs were used for qPCR: claudin1: forward, 5′-GGACAACATCG TGACTGCTC-3′ and reverse, 5′-CCCAGCAGG ATGCCAATTAC-3′; claudin2 …

National Medical Products Administration

Curiosity, Skepticism Over New Algae-Derived Alzheimer’s Drug | Medscape | 11/14/2019

National Medical Products Administration for mild-to-moderate AD. Oligomannate is a drug manufactured from an oligosaccharide extracted from marine algae and is the first novel drug approved for AD globally since 2003, the company said in a press release. It’s expected to be available in China by the end of the year. The drug works on the gut microbiome. It reportedly reconditions dysbiosis of gut microbiota, inhibits the abnormal …

Quintiles

Shanghai Green Valley announces NMPA approval of oligomannate for Mild to Moderate Alzheimer’s Disease | 11/8/2019

… the diagnosis of mild to moderate Alzhemer’s disease completed the study. The trial was conducted in collaboration with IQVIA (formally Quintiles) and Signant Health (formerly Bracket) among other partners. Trial results demonstrated that Oligomannate statistically … preclinical data “supports the emerging idea that modulation of the gut microbiome via treatments such as GV-971 or other strategies should be further explored as novel strategies to slow the progression of AD”. Green …

IQVIA

Shanghai Green Valley announces NMPA approval of oligomannate for Mild to Moderate Alzheimer’s Disease | 11/8/2019

… patients with the diagnosis of mild to moderate Alzhemer’s disease completed the study. The trial was conducted in collaboration with IQVIA (formally Quintiles) and Signant Health (formerly Bracket) among other partners. Trial results demonstrated that … preclinical data “supports the emerging idea that modulation of the gut microbiome via treatments such as GV-971 or other strategies should be further explored as novel strategies to slow the progression of AD”. Green …

Wolters Kluwer

Gut microbiome is altered by burns, affected by fluid resuscitation | 10/28/2019

Major burns lead to changes in the gastrointestinal tract bacteria, and these alterations of the gut microbiome are influenced by resuscitation with intravenous (IV) fluids, according to animal studies reported in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches , the official journal of the Shock Society. The journal is published in the Lippincott portfolio by Wolters Kluwer. Potentially disease-causing gut bacteria are increased after a major burn, while …

WebMD

Many Common Meds Could Alter Your Microbiome - WebMD | 10/23/2019

The gut microbiome includes at least 1,000 species of bacteria and is influenced by a number of different factors, including medication. Research suggests that changes in the gut microbiome are associated with obesity , diabetes, liver diseases , cancer and neurodegenerative diseases. “We already know that the efficiency and the toxicity of certain drugs are influenced by the bacterial composition of the gastrointestinal tract and that the gut microbiota has been related …

AbbVie

New evidence of a link between Parkinson’s disease and the gut could inspire treatments | FierceBiotech | 6/26/2019

… gut microbiome to treat Parkinson’s and autism. New York-based Kallyope is also leveraging the gut-brain axis to find small molecules for metabolic and neurological diseases. Targeting alpha-synuclein is also a popular strategy in Parkinson’s research. AbbVie and Voyager Therapeutics recently expanded their partnership to use “vectorize” antibodies against the toxic protein clump. A team at Georgetown University found that Novartis’ blood cancer drug Tasigna might work for …

Massachusetts General Hospital

Landmark Study Published in Nature Medicine and Presented at the American Society of Nutrition Shows Dietary Inflammation Varies Dramatically Among Healthy Adults, Pointing to the Need for Personalization in Eating | PR Newswire | 6/12/2020

… biology.” Study Details Led by Professor Tim Spector and his team at King’s College London and ZOE, in collaboration with Massachusetts General Hospital and additional researchers in the US, UK, Italy , Spain and Sweden , the … exists to understand the role of personalized nutrition and the gut microbiome to solve complex, food related health issues including chronic disease and metabolic syndrome. The studies are led by ZOE in collaboration with researchers …

Memorial Sloan Kettering

Memorial Sloan Kettering - Hackensack Meridian Health Partnership Announces Funding for Inaugural Immunology Research Collaboration Projects | PR Newswire | 6/5/2020

PRNewsfoto/Hackensack Meridian Health) (PRNewsfoto/John Theurer Cancer Center…) HACKENSACK, N.J. and NEW YORK As part of the Memorial Sloan Kettering – Hackensack Meridian Health Partnership, the two organizations have formed an Immunology Research Collaboration. Through … Sloan Kettering medical oncologist, is leading the project “Targeting the Gut Microbiome to Improve Outcomes after Allogeneic Hematopoietic Cell Transplantation.” This project will explore in an ongoing clinical trial whether certain antibiotics preserve specific anaerobic …

Meridian Health

Memorial Sloan Kettering - Hackensack Meridian Health Partnership Announces Funding for Inaugural Immunology Research Collaboration Projects | PR Newswire | 6/5/2020

PRNewsfoto/Hackensack Meridian Health) (PRNewsfoto/John Theurer Cancer Center…) HACKENSACK, N.J. and NEW YORK As part of the Memorial Sloan Kettering – Hackensack Meridian Health Partnership, the two organizations have formed an Immunology Research Collaboration. Through … Sloan Kettering medical oncologist, is leading the project “Targeting the Gut Microbiome to Improve Outcomes after Allogeneic Hematopoietic Cell Transplantation.” This project will explore in an ongoing clinical trial whether certain antibiotics preserve specific anaerobic …

Harvard Medical School

Synthetic Biologics Enters into Exclusive Option to License Intellectual Property for Use of SYN-020 to Treat and Prevent Age-Related Metabolic and Inflammatory Diseases | PR Newswire | 5/27/2020

… by Richard Hodin , MD, Chief of the Massachusetts General Hospital Division of General and Gastrointestinal Surgery and Professor of Surgery, Harvard Medical School , evaluated long-term oral supplementation of IAP, including SYN-020, in mice … the high therapeutic potential of IAP to promote GI and gut microbiome health,” said Steven A. Shallcross , Chief Executive and Financial Officer of Synthetic Biologics. “We are pleased to announce the expansion of our collaboration …

University Hospital

NORD Awards Eleven New Grants in Eight Disease States for Rare Disease Research | PR Newswire | 5/19/2020

… Effects of HIPEC on the Genetic Landscape of Peritoneal Metastases from High Grade Appendiceal Neoplasms Kjersti Flatmark, MD, PhD, Oslo University Hospital ( Oslo, Norway ); ctDNA for Monitoring Patients with Pseudomyxoma Peritonei For the study of … MD, New York University School of Medicine ( New York, NY ); Gut Microbiome Alterations as a Mechanism of Immune Dysregulation in New Onset Refractory Status Epilepticus For the study of primary orthostatic tremor , with funding from …

Northwestern Medicine

NORD Awards Eleven New Grants in Eight Disease States for Rare Disease Research | PR Newswire | 5/19/2020

… Ingo Helbig , MD, Children’s Hospital of Philadelphia ( Philadelphia, PA ); Beyond Negative Exome - Understanding the Genetics of FIRES Claude Steriade, MD and Deepak Saxena , MD, New York University School of Medicine ( New York, NY ); Gut Microbiome Alterations as a Mechanism of Immune Dysregulation in New Onset Refractory Status Epilepticus For the study of primary orthostatic tremor , with funding from public donations: Robert Chen, MA, MB BChir, MSc, Krembil Brain Institute, University …

Children's Hospital

NORD Awards Eleven New Grants in Eight Disease States for Rare Disease Research | PR Newswire | 5/19/2020

… Association, The David Ashwell Foundation and William Akers, Jr. & Georgia O. Akers Private Foundation, Inc.: Frances Flanagan , MBBCh, BAO, Boston Children’s Hospital ( Boston, MA ); Genetic Determinants of ACD/MPV For the study of appendix cancer … MD, New York University School of Medicine ( New York, NY ); Gut Microbiome Alterations as a Mechanism of Immune Dysregulation in New Onset Refractory Status Epilepticus For the study of primary orthostatic tremor , with funding from …

Medical Center

Dynamics of gut bacteria follow ecological laws | Phys Org | 5/13/2020

The seemingly chaotic bacterial soup of the gut microbiome is more organized than it first appears and follows some of the same ecological laws that apply to birds, fish, tropical rainforests, and even complex economic and financial markets, according to a new paper in Nature Microbiology by researchers at Columbia University Irving Medical Center. One of the main challenges facing researchers who study the gut microbiome is its sheer size …

Cedars-Sinai Medical Center

Synthetic Biologics Reports 2020 First Quarter Operational Highlights and Financial Results | PR Newswire | 5/5/2020

… sponsored clinical trial of SYN-010, intended to treat irritable bowel syndrome with constipation (IBS-C), being conducted out of Cedars-Sinai Medical Center (CSMC), as well as our planned Phase 1b /2a clinical trial … to reduce the impact of methane-producing organisms in the gut microbiome to treat an underlying cause of irritable bowel syndrome with constipation (IBS-C). The Company is also advancing SYN-020, an oral formulation …

MD Anderson Cancer Center

AI finds microbial signatures in tumours and blood across cancer types | 3/11/2020

… blood across cancers. Nadim J. Ajami & Nadim J. Ajami is in the Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA. Search for this author in: Google Scholar … microbes reside. This work has revealed a role for the gut microbiome in several types of cancer that arise in the intestinal lining itself 2 – 4 , and indicated that the gut microbiome might influence cancers …

Brigham and Women's Hospital

Trust Your Gut: How This Colombian Scientist Found Her Field | Forbes | 3/1/2020

… in microbiology – and she’s been focused on microbes ever since. Garcia-Bayona says when she joined the Comstock lab at Brigham and Women’s Hospital in Boston and Harvard Medical School they had a “very nice … Garcia-Bayon, Harvard Medical School/Brigham and Women’s Hospital “The gut microbiome plays a key role in human health and development, so it is one of the hottest research areas right now in the life …

Memorial Sloan Kettering Cancer Center

The Parker Institute for Cancer Immunotherapy Awards $2.75 Million to Support Six Early Career Researchers from Leading Research Institutions | PR Newswire | 2/26/2020

… of immunotherapy experts. PICI selected the early career researchers from leading research institutions in its network, including City of Hope, Memorial Sloan Kettering Cancer Center, the Perelman School of Medicine at the University of Pennsylvania … tumors that are resistant to current immunotherapies, particularly with the gut microbiome. She will explore new immunotherapy combinations with CAR T-cell therapies to overcome resistance in current treatments for patients with brain cancer. Kelly …

Mayo Clinic

Gastroenterology in 2030: What the specialty will look like in 10 years | Becker’s ASC Review | 12/19/2019

… 2030. Note: Responses were edited for style and content. Question: What will gastroenterology look like in 2030? Purna Kashyap, MBBS, Mayo Clinic (Rochester, Minn.): GI is evolving rapidly, making it a really exciting time for … both diagnostics as well as data-driven therapeutics targeting the gut microbiome. Artificial intelligence. The rapid accumulation of clinical, imaging and multiomics data has lured AI into GI, laying the path for precision medicine. [AI …

Johns Hopkins University School of Medicine

Treating multiple sclerosis with the help of the gut microbiome | FierceBiotech | 12/2/2019

… gut microbiome has been credited with producing an anti-inflammatory response in MS. Earlier this year, researchers from the University of California, San Francisco and the University of Toronto demonstrated that microbes in the gut activate plasma cells, which in turn produce anti-inflammatory antibodies in the central nervous system. Targeting the gut microbiome could prove useful in treating other brain diseases, like Parkinson’s. A team at the Johns Hopkins …

Providence St. Joseph Health

How Old Are You? Your Body Might Disagree With That Answer | PRWeb | 11/23/2019

… consent from program participants. This study builds on other important ISB findings, notably that the alpha diversity of an individual’s gut microbiome can be accurately predicted by examining metabolites in the blood, and that combining … in real-world clinical impacts. ISB is an affiliate of Providence St. Joseph Health, one of the largest not-for-profit health care systems in the United States. Share article on social media or email …

NYU Langone Health

Advances in Gut Microbiota of Viral Hepatitis Cirrhosis | 11/22/2019

… Institute of Infectious Disease, Peking University Ditan Teaching Hospital, Beijing, China 2 Division of Gastroenterology and Hepatology, Department of Medicine, NYU Langone Health, New York University School of Medicine, New York, NY, USA 3 Department … caused by long-term liver injury [ 1 ]. Recently, research about gut microbiome has emerged in liver disease fields. Samples are often derived from saliva, mucous, feces, and lavage fluids. A variety of study methods has …

Cleveland Clinic

NIH awards Cleveland Clinic $12 M to study link between gut microbes, heart disease | 11/19/2019

… Ph.D., Mark Brown, Ph.D., and their teams will continue to study the role of microbial pathways and cardiometabolic diseases Credit: Cleveland Clinic CLEVELAND: The National Institutes of Health has awarded more than $12 million to … first Program Project grants funded by NIH focused on the gut microbiome, a rapidly growing field that shows numerous links to human health and disease. The award is from the National Heart, Lung and Blood …

Michigan Medicine

E. coli gain edge by changing their diets in inflammatory bowel disease | Phys Org | 11/5/2019

… gut microbiome , composed of the trillions of bacteria that make their home inside the intestines, are key players. In a new paper in Nature Microbiology , Michigan Medicine researchers describe how bad bacteria gain a foothold over good bacteria in IBD and how something as simple as a diet change might reverse it. “The same bacteria are present in healthy and inflamed digestive tracts,” says Nobuhiko Kamada, Ph.D., of the division …

Union Hospital

Green Valley Announces NMPA Approval Of Oligomannate For Mild To Moderate Alzheimer’s Disease | PR Newswire | 11/3/2019

… Phase 3 clinical trial is a multicenter, randomized, double-blind, placebo-controlled, parallel-group 36 week study led by Peking Union Hospital and Shanghai Jiaotong University Medical School Mental Health Center. The study was conducted … preclinical data “supports the emerging idea that modulation of the gut microbiome via treatments such as GV-971 or other strategies should be further explored as novel strategies to slow the progression of AD”. Green …

Baylor College of Medicine

Could More Coffee Bring a Healthier Microbiome? | WebMD | 10/28/2019

New research that links caffeine consumption to a healthy gut microbiome – the trillions of microorganisms that live in your digestive tract and affect your overall health– may prompt you to pour generously. In recent years … Dr. Li Jiao, an associate professor of medicine-gastroenterology at Baylor College of Medicine in Houston. But her advice for now? “If you love coffee, enjoy it. Follow your gut.” The new findings were to …

Beth Israel Deaconess Medical Center

Metabolism And Gut Bacteria: What You Need To Know | 10/4/2019

… gut microbiome was for the first time studied comprehensively by researchers at Beth Israel Deaconess Medical Center (BIDMC). The human gut microbiome is a collective term used to refer to 1,000 odd bacteria inhabiting the gut, belonging to 160 bacteria species. This surprisingly has more of an impact on metabolism and obesity than one would imagine. Why is this? Diversity in the gut bacteria becomes compromised with a high intake …

Angus Liu

Insights into how Novo Nordisk’s Saxenda cuts food cravings may inspire new obesity drugs | FierceBiotech | 3/5/2020

Insights into how Novo Nordisk’s Saxenda cuts food cravings may inspire new obesity drugs by Angus Liu Mar 5, 2020 7:32am Studies in rats showed that Novo Nordisk’s GLP-1 obesity drug Saxenda interacts with … suppressing effects. RELATED: Kintai’s obesity drug that works via the gut microbiome moves closer to the clinic The liraglutide finding adds to a growing body of discoveries by UPenn scientists related to obesity. Another team …

Mark Smith

Drugs From Bugs: Why Gates, Zuck And Benioff Think The Next Blockbusters Will Come From Inside Your Gut | Forbes | 2/7/2020

… prone to C. diff since antibiotic treatment for other maladies decimates the infection-fighting capacity of what scientists call the gut microbiome, the trillions of cells that move through the human digestive system. “It didn’t … one of the most promising startups developing microbiome drugs. Cofounder Mark Smith, 33, was a microbiology grad student at MIT when the 20-something C. diff patient begged him for help. “I had to tell …

Donald Trump

Science X Newsletter Wednesday, Jan 22 | 1/23/2020

… events Suppression of newly found protein could lead to future treatments to slow Alzheimer’s progression Persistent environmental contaminant changes the gut microbiome of mice Researchers test cells with silicon anodes, alumina coatings that protect cathodes … has to help’ on police access to encrypted phones President Donald Trump weighed in Wednesday on Apple’s dispute with the US government over giving law enforcement access to encrypted iPhones, saying the company “has to …

Alex Stevenson

Clinical Update - 4D Announce New Study of MRx0518 in Pancreatic Cancer | PR Newswire | 1/6/2020

… gut microbiome. Alex Stevenson , 4D’s Chief Scientific Officer, commented: “Pancreatic cancer carries a poor prognosis and remains an area of significant unmet need. Encouraged by promising early signals in our other clinical studies, we believe MRx0518 has the potential to offer new treatment options and dramatically improve outcomes for patients with pancreatic cancer. This third study demonstrates 4D’s ongoing commitment to oncology.” 4D recently announced clinical observations from its ongoing …

Michael Greger

Physician and New York Times Bestselling Author Dr. Michael Greger Officially Releases New Sustainable Weight Loss Book - HOW NOT TO DIET | PR Newswire | 12/10/2019

WASHINGTON , Dec. 10, Dr. Michael Greger , M.D., FACLM, the internationally-renowned nutrition expert, physician, founder of Nutritionfacts.org, and author of the bestselling book How Not to Die , has turned his attention to the latest research … the insulin index, and the impact of foods on the gut microbiome—showing how plant-based eating is crucial to overall health. How Not to Diet goes beyond food to identify twenty-one weight-loss …

Jeffrey Cummings

Alzheimer’s experts greet China’s surprise approval of a drug for brain disease with hope and caution | Science | AAAS | 11/5/2019

… and drug developers with a new plant-based compound it claims improves cognitive function in Alzheimer’s patients by altering their gut microbiomes. In mouse studies published earlier this year, this approach reduced inflammation in the … anywhere in the world for Alzheimer’s disease since 2003,” says Jeffrey Cummings, an Alzheimer’s researcher at the University of Nevada in Las Vegas, who is advising the drug’s developer, Shanghai, China–based Green Valley Pharmaceutical …

Kevin Ho

BiomeSense Nabs $2M to Expand Daily Gut Microbiome Tracking Platform | HIT Consultant | 10/4/2019

BiomeSense raises $2M in seed funding to expand its biosensor and analytics platform for daily gut microbiome tracking. – The company is working on completing its prototype biosensor and data modeling platform in preparation for the … and SOSV . Enabling Continuous Microbiome Testing Founded in 2018 by Kevin Honaker and Dr. Jack Gilbert, BiomeSense is developing an at-home biosensor to produce continuous gut microbiome data and a cloud-based analytics platform …

Naveen Jain

Viome Named to the 2019 CB Insights Digital Health 150, List of Most Innovative Digital Health Startups | Globe Newswire | 10/3/2019

… optional by understanding the root cause of chronic diseases and pinpointing methods of prevention, beginning with the analysis of the gut microbiome. Viome applies advanced sequencing technology developed at the Los Alamos National Lab to … as ‘incurable’ for so long,” said Viome CEO and Founder Naveen Jain. “Viome is on a mission to challenge traditional healthcare perceptions and practices, and this acknowledgment from CB Insights validates that we’re on the …

Anand Sanwal

Viome Named to the 2019 CB Insights Digital Health 150, List of Most Innovative Digital Health Startups | Globe Newswire | 10/3/2019

… optional by understanding the root cause of chronic diseases and pinpointing methods of prevention, beginning with the analysis of the gut microbiome. Viome applies advanced sequencing technology developed at the Los Alamos National Lab to … our ambitious goals in the years ahead.” CB Insights CEO Anand Sanwal revealed the final Digital Health 150 during Future of Health, a gathering of top executives across some of the largest healthcare institutions, startups …

Ken Blount

Microbiome Therapeutics Innovation Group Highlights Member Company Activity at IDWeek 2019 | PR Newswire | 10/1/2019

… IDWeek is one of the premier conferences each year that showcases the advancements and innovations aimed at helping patients,” said Ken Blount , Chief Scientific Officer of Rebiotix (a Ferring company) and MTIG Chair. “Many of … Recurrent Clostridioides difficile (C. Difficile) infection (rCDI), Stably Restores the Gut Microbiome after Vancomycin (Vanco)-Induced Dysbiosis in Adult Healthy Volunteers (HV) Time: 11:00 a.m. to 11:15 a.m. About The Microbiome Therapeutics Innovation Group The …

Jessica Richman

Oops—Layoffs of lab staff at uBiome force the company to halt sample testing: reports | FierceBiotech | 7/11/2019

… report from Business Insider . The indefinite pause affects uBiome’s sole remaining offering—its direct-to-consumer Explorer test, which examines gut microbiome bacteria to provide information on wellness, food and lifestyle choices. uBiome previously halted … following FBI raid uBiome’s pair of founders and co-CEOs, Jessica Richman and Zac Apte, were placed on administrative leave in early May following the FBI’s search of its headquarters, where officers confiscated computers and …

Heiko Braak

New evidence of a link between Parkinson’s disease and the gut could inspire treatments | FierceBiotech | 6/26/2019

… travel from the gut to the brain. They published the findings in the journal Neuron. Back in 2003, German neuroanatomist Heiko Braak and colleagues found that in postmortem samples of Parkinson’s patients, clumps of alpha … netted $25 million to fund its programs that target the gut microbiome to treat Parkinson’s and autism. New York-based Kallyope is also leveraging the gut-brain axis to find small molecules for metabolic and …