Disease Registry

Feeding the Waste Cycle: How PFAS ‘Disposal’ Perpetuates Contamination | 8/18/2020

… or in laboratory animal studies ● Moderate evidence of health effect documented in people or in laboratory animal studies ▲ Not studied or no reported association in available studies Sources: The Agency for Toxic Substances and Disease Registry ; the National Toxicology Program ; Environmental Protection Toxicity Assessments for PFBS and GenX ; and other sources from the peer-reviewed scientific literature. Incineration The carbon-fluorine bonds in PFAS are among the strongest chemical structures …

How fish smoking endangers humans, causes deforestation | 8/17/2020

… in Nigeria lament inability to sell the products locally as the COVID-19 impacts on the economy bites harder. How toxic contents in firewood, charcoal cause cancer, pollution The Agency for Toxic Substances and Disease Registry (ATSDR), Atlanta, Georgia, of the U.S. Department of Health and Human Services, says Polycyclic Aromatic Hydrocarbons (PAHs) are a group of over 100 different chemicals that are formed during the incomplete burning of coal …

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ATSDR’s Toxic Substances Portal | 8/17/2020

… to find information about toxic chemicals and related health effects. Learn how toxic substances can affect health and how to prevent exposure. The Environmental Protection Agency (EPA) and the Agency for Toxic Substances and Disease Registry (ATSDR) prepare the National Priority List (NPL) which is a “list of national priorities among the known releases or threatened releases of hazardous substances, pollutants, or contaminants throughout the United States and its territories …

COVID-19: Packaged Fast-Food Pollutants Are Only the Beginning | 8/15/2020

… the food that has been bought from them. Researchers have linked PFAS to very concerning medical issues including cancers and birth defects in animals and humans. According to the Agency for Toxic Substances and Disease Registry studies, PFASs have been linked to kidney and testicular cancer, thyroid disease, liver damage, fertility issues, and pregnancy-induced hypertension/preeclampsia, changes in fetal and childhood development, increased risk of asthma, negative changes in …

The effect of oral sildenafil therapy on health-related quality of life in adults with pulmonary arterial hypertension related to uncorrected secundum atrial septal defect: a quasi experimental study | 8/14/2020

… Uncorrected left to right shunt may increase pulmonary pressure and lead to vascular remodeling and dysfunction. Thus, it is responsible for progressive increase of pulmonary vascular resistance and right heart pressure [ 1 ]. Based on disease registry of PAH on ASD patients in Sardjito General Hospital Yogyakarta, out of 123 adult ASD patients, 74% among them had PAH [ 2 ]. Post (2013) mentioned that PAH was found in 9–35% secundum ASD …

Physicians for Informed Consent Publishes New Educational Document on Risk of Aluminum in Vaccines | PRWeb | 8/13/2020

… doses of aluminum-containing vaccines are recommended to children, with 11 doses recommended from birth to 6 months of age. The U.S. Food and Drug Administration (FDA) and the Agency for Toxic Substances and Disease Registry (ATSDR), agencies of the U.S. Department of Health and Human Services (HHS), have raised concerns about the negative effects of aluminum exposure in humans. In scientific studies, small amounts of aluminum that remain in …

Medium-Term Complications Associated With Coronary Artery Aneurysms After Kawasaki Disease: A Study From the International Kawasaki Disease Registry | 8/11/2020

Background Coronary artery aneurysms (CAAs) may occur after Kawasaki disease (KD) and lead to important morbidity and mortality. As CAA in patients with KD are rare and heterogeneous lesions, prognostication and risk stratification are difficult. We sought to derive the cumulative risk and associated factors for cardiovascular complications in patients with CAAs after KD. Methods and Results A 34-institution international registry of 1651 patients with KD who had CAAs …

KCDPH works to update COVID-19 data | News | hanfordsentinel.com | 8/11/2020

… hopes to have updated COVID-19 information as soon as possible. In early August, the California Department of Public Health discovered technology issues with the electronic laboratory reporting system which reports into the state’s disease registry system, known as CalREDIE, likely causing an underreporting of COVID-19 cases. It’s estimated that 250,000-300,000 records were backlogged, with most but not all related to COVID-19. Officials said COVID-19 cases may …

The End Is Nearer for ‘Forever Chemicals’ in Food Wrappers | 8/8/2020

2 VIEWS While other PFAS haven’t been as well-studied, that isn’t the same as giving them a green light. FDA scientists who analyzed industry data on 6:2 FTOH and its metabolites reported signs of immune effects in rodents. This summer, the Agency for Toxic Substances and Disease Registry , a part of the CDC, issued a “ statement on potential intersection between PFAS and Covid-19 .” The agency noted that “little …

‘Broken’ coronavirus tracking system leaves California in the dark: ‘We have no idea’ | LA Times | 8/7/2020

… restrictions lifted until the system is fixed. State officials have not yet provided details on when fixes will be made to the electronic system, called CalREDIE, that reports coronavirus test results to the state’s disease registry system. California, as a result, lacks an accurate count of coronavirus infections, leading health officials to freeze the state’s watchlist, with no counties added or removed. “CalREDIE has broken,” said Peter Beilenson, director of …

‘Broken’ COVID-19 tracking leaves California with ‘no idea’ | 8/7/2020

… lifted until the the system is fixed. State officials have not yet provided details on when fixes will be made to the electronic system, called CalREDIE, that reports coronavirus test results to the state’s disease registry system. California, as a result, lacks an accurate count of coronavirus infections, leading health officials to freeze the state’s watchlist, with no counties added or removed. “CalREDIE has broken,” said Peter Beilenson, director of …

Bay Area COVID-19 hospitalizations appear to be leveling off - SFGate | 8/6/2020

… Here’s a county-by-county look at hospitalization figures. All data comes from individual county websites and the state’s database for county-by-county hospitalizations. Due to an ongoing technical issue with the state’s disease registry system CalREDIE, SFGATE is not reporting the test positivity rate this week. State and county officials have stated the glitch is creating inaccurate estimates for case and test positivity metrics. San Francisco (7,081 confirmed …

California Health Department reveals underreporting of COVID-19 cases | 8/6/2020

… underreporting of the number of increases in COVID-19 cases every day due to technical glitch with the electronic laboratory reporting systems. According to CPDH, the electronic laboratory systems directly reports into the California Disease Registry System (CalREDIE). The technical problems do not affect COVID-19 hospitalizations and death rates, which are reported to the state through a different system. The health department also stated that the issues do not …

Placer County COVID-19 Positivity Rate Soars | 8/6/2020

… website, Placer County’s 7-day positivity rate currently stands at 11 %, off a recent high of 14.6%. County officials noted the higher rates were artificially inflated due to to incomplete datasets from the state’s disease registry . The testing rate per 100,000 residents in Placer ranks among the lower tier with some reporting long delays in getting results. Placer County officials continue to report ICU beds in short supply on the …

Glitches in California’s infectious disease reporting system lead to ‘significant’ COVID-19 undercount | 8/5/2020

Twitter Volunteers wearing PPE at Flynn Elementary COVID-19 testing site, April 25. Photo by Lola M. Chavez Weeks-long glitches plaguing CalREDIE, the California infectious disease registry system have led to crippling delays in information filtering back to counties — and a “significant” undercount in COVID-19 cases. Gov. Gavin Newsom yesterday spoke of “encouraging” and “early good signs” regarding coronavirus infection rates. But officials in multiple California counties told …

CDPH Update on Data Reporting | 8/5/2020

Print advertisement August 4, 2020 – CDPH has discovered an underreporting of COVID-19 cases due to technology issues with the electronic laboratory reporting system which reports into the state’s disease registry system (CalREDIE). However, patient care and test results are not affected or delayed by this issue. Laboratories continue to report test results directly to providers and hospitals, and hospitalization and death rates are not impacted as they are reported …

County of Ventura COVID-19 Update for Aug. 4 — Community Forum on Aug. 5 | 8/5/2020

… Public Health (CDPH) at by clicking here. Info from CDPH CDPH has discovered an underreporting of COVID-19 cases due to technology issues with the electronic laboratory reporting system which reports into the state’s disease registry system (CalREDIE). However, patient care and test results are not affected or delayed by this issue. Laboratories continue to report test results directly to providers and hospitals, and hospitalization and death rates are not …

Issues arise with COVID-19 case reporting system | News | hanfordsentinel.com | 8/5/2020

… reporting system, according to the California Department of Public Health. “CDPH has discovered an underreporting of COVID-19 cases due to technology issues with the electronic laboratory reporting system which reports into the state’s disease registry system (CalREDIE),” the department announced Tuesday. Ed Hill, director of the Kings County Department of Health, said state representatives verified the issues to his department over the weekend. “Because of this we are not …

EPA Week in Review: PFAS Edition | 8/1/2020

… agencies within the federal family, understanding the health effects of exposures to PFAS continues to be a priority for the Centers for Disease Control and Prevention (CDC) and the Agency for Toxic Substances and Disease Registry (ATSDR),” said Dr. Robert Redfield, Director of the CDC and Administrator of ATSDR. “This virtual workshop with the National Academies is a welcomed opportunity to discuss and contribute to the growing body of knowledge …

This Clear Face Mask on Etsy Has Over 1,400 5-Star Reviews | Yahoo News | 7/31/2020

… or even teachers in a classroom, explains Robert Amler, M.D. , the vice president for government affairs at New York Medical College and former CDC chief medical officer on the Agency for Toxic Substances and Disease Registry . “Even people who are not hard of hearing can understand you better when you’re speaking and they can see your mouth moving,” Dr. Amler says, adding that smiles, grimaces, or other facial expressions are …

Yellow Prussiate of Soda, a Cyanide-Containing Salt Additive, Is Vegan | 7/31/2020

… on an ingredient label as sodium ferrocyanide decahydrate. Other ways the name appears on a label are possible. NOTE: Inhalation or ingestion of cyanide salts can be fatal. The Agency for Toxic Substances and Disease Registry (ATSDR) states: “Ingestion of hydrogen cyanide solutions or cyanide salts can be rapidly fatal…Treatment of ingested cyanide salts is similar to treatment of oral hydrogen cyanide poisoning because cyanide salts form hydrogen cyanide …

catdragonunicorn: moonlightmarathon: chaos-and-cookies: vidramon: automaticdestinydelusion: bea-… | 7/30/2020

… the testing indicate that both scented and unscented Always pads emit toxic chemicals, including chemicals identified by the U.S. Department of Health and Human Services National Toxicology Program, the Agency for Toxic Substances and Disease Registry , and the State of California Environmental Protection Agency as carcinogens , and reproductive and developmental toxins. None of these chemicals are disclosed on the product by the manufacturer.” (x) I switched to dye free fancy …

New study to assess local PFAS exposure | 7/29/2020

The Centers for Disease Control and Prevention (CDC) and the Agency for Toxic Substances and Disease Registry (ATSDR) just announced the initiation of an exposure assessment in the Security-Widefield area. The purpose of the assessment is to provide information to the community members about the levels of per- and polyfluoroalkyl substances (PFAS) in their bodies and provide information about exposures in the broader community. What: CDC and ATSDR scientists …

Meritor, Inc. v. Environmental Protection Agency | 7/28/2020

… 1 See United States EPA, Toluene (2016), https://www.epa.gov/ sites/production/files/2016-09/documents/toluene.pdf; United States EPA, Trichloroethylene (2016), https://www.epa.gov/sites/ production/files/2016-09/documents/trichloroethylene.pdf.; see also Agency for Toxic Substances & Disease Registry , 1,2Dichloroethene (1996), https://www.atsdr.cdc.gov/phs/phs. asp?id=462&tid=82 (discussing the potential adverse health effects of cis-1,2-dichloroethene). 6 That same year, Meritor installed a sub-slab depressurization system below the …

moonlightmarathon: chaos-and-cookies: vidramon: automaticdestinydelusion: bea-sayan: thestormalwa… | 7/27/2020

… the testing indicate that both scented and unscented Always pads emit toxic chemicals, including chemicals identified by the U.S. Department of Health and Human Services National Toxicology Program, the Agency for Toxic Substances and Disease Registry , and the State of California Environmental Protection Agency as carcinogens , and reproductive and developmental toxins. None of these chemicals are disclosed on the product by the manufacturer.” (x) I switched to dye free fancy …

Food and Drug Administration

Physicians for Informed Consent Publishes New Educational Document on Risk of Aluminum in Vaccines | PRWeb | 8/13/2020

Food and Drug Administration (FDA) and the Agency for Toxic Substances and Disease Registry (ATSDR), agencies of the U.S. Department of Health and Human Services (HHS), have raised concerns about the negative effects of aluminum exposure in humans. In scientific studies, small amounts of aluminum that remain in the body have been observed to interfere with a variety of cellular and metabolic processes in the nervous system and in tissues …

Physicians for Informed Consent Publishes New Educational Document on Risk of Aluminum in Vaccines | PRWeb | 8/13/2020

Food and Drug Administration (FDA) and the Agency for Toxic Substances and Disease Registry (ATSDR), agencies of the U.S. Department of Health and Human Services (HHS), have raised concerns about the negative effects of aluminum exposure in humans. In scientific studies, small amounts of aluminum that remain in the body have been observed to interfere with a variety of cellular and metabolic processes in the nervous system and in tissues …

Department of Health and Human Services

Physicians for Informed Consent Publishes New Educational Document on Risk of Aluminum in Vaccines | PRWeb | 8/13/2020

Disease Registry (ATSDR), agencies of the U.S. Department of Health and Human Services (HHS), have raised concerns about the negative effects of aluminum exposure in humans. In scientific studies, small amounts of aluminum that remain in the body have been observed to interfere with a variety of cellular and metabolic processes in the nervous system and in tissues of other parts of the body. Some of the most damaging effects …

Physicians for Informed Consent Publishes New Educational Document on Risk of Aluminum in Vaccines | PRWeb | 8/13/2020

Disease Registry (ATSDR), agencies of the U.S. Department of Health and Human Services (HHS), have raised concerns about the negative effects of aluminum exposure in humans. In scientific studies, small amounts of aluminum that remain in the body have been observed to interfere with a variety of cellular and metabolic processes in the nervous system and in tissues of other parts of the body. Some of the most damaging effects …

CDC

This Clear Face Mask on Etsy Has Over 1,400 5-Star Reviews | Yahoo News | 7/31/2020

CDC chief medical officer on the Agency for Toxic Substances and Disease Registry. “Even people who are not hard of hearing can understand you better when you’re speaking and they can see your mouth moving,” Dr. Amler says, adding that smiles, grimaces, or other facial expressions are key in many settings. “[Expressions] is also part of our communication, and some may be a lot happier working and living together in …

Ex-CDC Boss Says ‘There Are Things That Are Clearly Missing’ From White House Reopening Guidelines | Newsweek | 4/18/2020

CDC and the U.S. Agency for Toxic Substances and Disease Registry over the first six months of the Obama administration, said in an interview with Newsweek that the guidelines unveiled by the White House on Thursday have significant gaps that could render them an ineffective metric for whether states truly have COVID-19 under control. “There are things in there that are very encouraging in terms of wanting to see …

Clinical Research

Research Assistant, Clinical Neurosciences, Cumming School of Medicine | University of Calgary | 11/20/2019

… Disease Registry. The Canadian Neuromuscular Disease Registry is recruiting a Research Assistant to accelerate our various national scale clinical research projects. We are looking for someone who is eager to take advantage of the opportunities for personal growth inherent in our research network while at the same time producing outstanding results for our team. The ideal candidate will bring both the attention to detail needed for the routine aspects of …

Eloxx Pharmaceuticals Reports Third Quarter 2019 Financial and Operating Results and Provides Business Update | Globe Newswire | 11/5/2019

… Dr. Thomas Haverty as our Chief Medical Officer. Dr. Haverty has over 30 years of pharmaceutical and biotechnology experience leading clinical research and operations teams with responsibility for large development portfolios in virtually all classes … Foundation Fighting Blindness (FFB) to support its inherited retinal degenerative disease registry and educational programs. In October 2019, we presented as part of the FFB New York Vision Seminar and we believe that the ongoing …

Mental Health

State Highlights: Civil Trial Begins For Arizona Body Donation Facility Accused Of Fraud; Experts Link High Lung Cancer Rates In Missouri, Kentucky With Smoking | Kaiser Health News | 11/13/2019

… linked to an increase cancer risk. WXIA-TV reports some Covington residents are asking the Agency for Toxic Substances and Disease Registry to investigate cases near the plant, which has released leaked ethylene oxide into … SF Mayor Breed, Supervisors Agree On Plan To Overhaul City’s Mental Health Program San Francisco Mayor London Breed and Supervisors Matt Haney and Hillary Ronen announced a deal Tuesday reconciling their dueling plans to reform …

What’s in your water: A Congressional briefing | 10/25/2019

… Environmental Health and the Agency for Toxic Substance and Disease Registry at the Centers Prevention, helped lead the response to water contamination in Flint, Michigan. He joined other public health experts at the briefing on the role of federal, state and local agencies in tackling water contaminants in the U.S. The “What’s in Your Water” briefing took place on Capitol Hill and was co-sponsored by APHA and other groups …

Medical Research

First Edition: November 13, 2019 | Kaiser Health News | 11/13/2019

… remains would be used. The suit alleges the facility committed fraud by claiming the donated bodies would be used for medical research, when in at least two cases it knew the human remains would be … Covington residents are asking the Agency for Toxic Substances and Disease Registry to investigate cases near the plant, which has released leaked ethylene oxide into the surrounding air. (11/12) This is part of the KHN …

State Highlights: Civil Trial Begins For Arizona Body Donation Facility Accused Of Fraud; Experts Link High Lung Cancer Rates In Missouri, Kentucky With Smoking | Kaiser Health News | 11/13/2019

… remains would be used. The suit alleges the facility committed fraud by claiming the donated bodies would be used for medical research, when in at least two cases it knew the human remains would be … Covington residents are asking the Agency for Toxic Substances and Disease Registry to investigate cases near the plant, which has released leaked ethylene oxide into the surrounding air. (11/12) Boston Globe: Conrad Roy’s Mother Urges …

Clinical Data

Preoperative and Postoperative Bone Mineral Density Change and Risk Factor Analysis in Patients with a GH-Secreting Pituitary Adenoma | 11/3/2019

… Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China 2 China Pituitary Disease Registry Center, Chinese Pituitary Adenoma Cooperative Group, Beijing 100730, China 3 Key Laboratory of … BMD changes and explored risk factors associated with BMD. Methods . Clinical data of 39 patients with growth hormone- (GH-) secreting pituitary adenomas and 29 patients with nonfunctioning pituitary adenomas who were newly diagnosed in neurosurgery …

Clinical Data Associate III — G3873A : Data Science & Informatics 5100 (19-00940) – MA – Cambridge | 10/22/2019

by admin Clinical Data Associate III — G3873A : Data Science & Informatics 5100 (19-00940) – MA – Cambridge The Clinical Data Associate III position is part of the Data Management Technical Team, which is a sub-group of the overall Registry Data Management group. This position is a technical individual dedicated to operational activities related to the technical development, implementation, and maintenance of Client’s Global Rare Disease Registry web-based electronic data capture (EDC …

Medline

Blood Tests Show Exposure to Ethylene Oxide | WebMD | 12/10/2019

… be used to inform health reports for area residents that are being compiled by the Agency for Toxic Substances and Disease Registry, a specialized division of the CDC that analyzes risks to communities from environmental … two facilities that release ethylene oxide: Vantage Specialty Chemicals and Medline Industries. Vantage uses the chemical to make household and industrial products. Medline packages surgical kits, then uses ethylene oxide gas to sterilize them. A …

Blood Tests Show Exposure to Ethylene Oxide | WebMD | 12/9/2019

… be used to inform health reports for area residents that are being compiled by the Agency for Toxic Substances and Disease Registry, a specialized division of the CDC that analyzes risks to communities from environmental … two facilities that release ethylene oxide: Vantage Specialty Chemicals and Medline Industries. Vantage uses the chemical to make household and industrial products. Medline packages surgical kits, then uses ethylene oxide gas to sterilize them. A …

Sterigenics

Illinois veto session primer: With few overrides to consider, new proposals take forefront | State/Region | thesouthern.com | 10/27/2019

… Sterigenics, a medical supply sterilization plant linked to an “elevated cancer risk” in the Willowbrook area by the federal Agency for Toxic Substance and Disease Registry, to abandon its plans to reopen. Chicago, gambling issues Chicago mayor: To balance budget, city ‘will need cooperation from Springfield’ In her budget address this week, Chicago Mayor Lori Lightfoot called on state lawmakers to authorize the city to increase its real estate transfer …

New proposals take forefront at veto session | 10/27/2019

… Sterigenics, a medical supply sterilization plant linked to an “elevated cancer risk” in the Willowbrook area by the federal Agency for Toxic Substance and Disease Registry, to abandon its plans to reopen. Chicago, gambling issues In her budget address this week, Chicago Mayor Lori Lightfoot called on state lawmakers to authorize the city to increase its real estate transfer tax, to “support a Chicago casino,” and to “develop a statewide …

Andrew Wheeler

Southern States Split in Response to EPA’s Coal Ash Rule Rollbacks - The Pew Charitable Trusts | 12/2/2019

… has had other ideas. At first, it delayed Obama regulations from fully going into effect. Now, Environmental Protection Agency Administrator Andrew Wheeler, a former coal lobbyist, has proposed softening rules that aim to limit the … from the EPA and the Agency for Toxic Substances and Disease Registry. Most of America’s ponds are unlined and contain contamination groundwater at levels that surpass federal standards, according to an analysis by the environmental …

Southern States Split in Response to EPA’s Coal Ash Rule Rollbacks | 12/2/2019

… has had other ideas. At first, it delayed Obama regulations from fully going into effect. Now, Environmental Protection Agency Administrator Andrew Wheeler, a former coal lobbyist, has proposed softening rules that aim to limit the … from the EPA and the Agency for Toxic Substances and Disease Registry. Most of America’s ponds are unlined and contain contamination groundwater at levels that surpass federal standards, according to an analysis by the environmental …

Jeanne Shaheen

Information session on Pease PFAS health study on Oct. 24 | 10/22/2019

PORTSMOUTH — The Agency for Toxic Substances and Disease Registry and the Centers for Disease Control and Prevention will host a community information session on the upcoming Pease Study: PFAS Health Effects on Thursday Oct. 24. U.S. Sen. Jeanne Shaheen on Oct. 11 announced the creation of a national health study, proposed by her legislation, of people exposed to human-made chemicals per- and polyfluoroalkyl substances. A pilot study will focus …

Study on effects of PFAS contamination set to launch at Pease | 10/12/2019

… Jeanne Shaheen.The Centers for Disease Control and Prevention and the Agency for Toxic Substances and Disease Registry officials joined others Friday to discuss the launch of the study.”To be here today at the start of a health study after five years of working really hard towards this is a really powerful moment for me,” said Andrea Amico, co-founder of Testing for Pease.Researchers hope to include 1,000 adults and …

Rick Snyder

Michigan scrambles to address chemical contaminants in water | Phys Org | 12/30/2017

Rick Snyder created a state response team and approved $23 million in emergency spending. The chemicals do not break down easily and can migrate from soil to groundwater. They were used in scores of U.S. industrial applications and have been detected in human and animal blood around the globe. The Agency for Toxic Substances and Disease Registry says scientists are uncertain about how they affect human health at exposure levels …

Michigan scrambles to address chemical contaminants in water | Yahoo News | 12/30/2017

Rick Snyder created a state response team and approved $23 million in emergency spending. The chemicals do not break down easily and can migrate from soil to groundwater. They were used in scores of U.S. industrial applications and have been detected in human and animal blood around the globe. The Agency for Toxic Substances and Disease Registry says scientists are uncertain about how they affect human health at exposure levels …

Washington, District of Columbia

Coronavirus, SARS and Flu Resources | 6/19/2020

… Coronavirus Situation Summary and Resources CDC: COVIDView – A Weekly Surveillance of COVID-19 Activity CDC: Agency for Toxic Substances and Disease Registry Johns Hopkins Coronavirus Map Johns Hopkins Coronavirus Data NY Times Graphics: Tracking the … daily cases). Institute for Health Metrics and Evaluation University of Washington compiles data on causes of death, hospital bed availability and more. Global Infectious Diseases and Epidemiology Network Data, endemicity maps, detailed notes and more …

Coronavirus and COVID-19 Data and Research | 6/19/2020

… Coronavirus Situation Summary and Resources CDC: COVIDView – A Weekly Surveillance of COVID-19 Activity CDC: Agency for Toxic Substances and Disease Registry Johns Hopkins Coronavirus Map Johns Hopkins Coronavirus Data NY Times Graphics: Tracking the … daily cases). Institute for Health Metrics and Evaluation University of Washington compiles data on causes of death, hospital bed availability and more. Global Infectious Diseases and Epidemiology Network Data, endemicity maps, detailed notes and more …